PDB entry 4na5

View 4na5 on RCSB PDB site
Description: Crystal structure of mouse poly(ADP-ribose) glycohydrolase (PARG) catalytic domain mutant E748N
Class: hydrolase
Keywords: Poly(ADP-ribose) glycohydrolase, hydrolase
Deposited on 2013-10-21, released 2014-01-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-09-24, with a file datestamp of 2014-09-19.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.182
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Poly(ADP-ribose) glycohydrolase
    Species: Mus musculus [TaxId:10090]
    Gene: parG
    Database cross-references and differences (RAF-indexed):
    • Uniprot O88622
      • engineered mutation (310)
    Domains in SCOPe 2.08: d4na5a_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4na5A (A:)
gnlppekkwlgtpieemrkmprcgihlpslrpsashtvtvrvdllragevpkpfpthykd
lwdnkhvkmpcseqnlypvedengertagsrweliqtallnkftrpqnlkdailkynvay
skkwdftalvdfwdkvleeaeaqhlyqsilpdmvkialclpnictqpipllkqkmnhsvt
msqeqiasllanaffctfprrnakmkseyssypdinfnrlfegrssrkpeklktlfcyfr
rvtekkptglvtftrqsledfpewercekpltrlhvtyegtiegngrgmlqvdfanrfvg
ggvtgaglvqneirflinpelivsrlftevldhnecliitgteqyseytgyaetyrwars
hedgsekddwqrrcteivaidalhfrryldqfvpekvrrelnkaycgflrpgvpsenlsa
vatgnwgcgafggdarlkaliqilaaaaaerdvvyftfgdselmrdiysmhtflterkld
vgkvyklllryyneecrncstpgpdiklypfiyhavessaet

    Sequence, based on observed residues (ATOM records): (download) 
    >4na5A (A:)
pekkwlgtpieemrkmprcgihlpslrpsashtvtvrvdllragevpkpfpthykdlwdn
khvkmpcseqnlypvtagsrweliqtallnkftrpqnlkdailkynvayskkwdftalvd
fwdkvleeaeaqhlyqsilpdmvkialclpnictqpipllkqkmnhsvtmsqeqiaslla
naffctfprrnakmkseyssypdinfnrlfegrssrkpeklktlfcyfrrvtekkptglv
tftrqsledfpewercekpltrlhvtyegtiegngrgmlqvdfanrfvgggvtgaglvqn
eirflinpelivsrlftevldhnecliitgteqyseytgtyrwarshedgsekddwqrrc
teivaidalhfrryldqfvpekvrrelnkaycgflrpgvpsenlsavatgnwgcgafggd
arlkaliqilaaaaaerdvvyftfgdselmrdiysmhtflterkldvgkvyklllryyne
ecrncstpgpdiklypfiyhavess