PDB entry 4n8v

View 4n8v on RCSB PDB site
Description: Crystal structure of killer cell immunoglobulin-like receptor KIR2DS2 in complex with HLA-A
Deposited on 2013-10-18, released 2014-02-05
The last revision was dated 2014-03-12, with a file datestamp of 2014-03-07.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.224
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, A-11 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • expression tag (0)
  • Chain 'C':
    Compound: peptide from Virion membrane protein A14
    Species: Vaccinia virus WR, synthetic [TaxId:10254]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: HLA class I histocompatibility antigen, A-11 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: peptide from Virion membrane protein A14
    Species: Vaccinia virus WR, synthetic [TaxId:10254]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: killer cell immunoglobulin-like receptor 2ds2
    Species: Homo sapiens [TaxId:9606]
    Gene: KIR2DS2
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: killer cell immunoglobulin-like receptor 2ds2
    Species: Homo sapiens [TaxId:9606]
    Gene: KIR2DS2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >4n8vA (A:)
gshsmryfytsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dqetrnvkaqsqtdrvdlgtlrgyynqsedgshtiqimygcdvgpdgrflrgyrqdaydg
kdyialnedlrswtaadmaaqitkrkweaahaaeqqraylegrcvewlrrylengketlq
rtdppkthmthhpisdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgeeqrytchvqheglpkpltlrw

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >4n8vB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >4n8vC (C:)
mliysmwgk

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >4n8vD (D:)
gshsmryfytsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dqetrnvkaqsqtdrvdlgtlrgyynqsedgshtiqimygcdvgpdgrflrgyrqdaydg
kdyialnedlrswtaadmaaqitkrkweaahaaeqqraylegrcvewlrrylengketlq
rtdppkthmthhpisdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgeeqrytchvqheglpkpltlrw

  • Chain 'E':
    Sequence, based on SEQRES records:
    >4n8vE (E:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records):
    >4n8vE (E:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records:
    >4n8vF (F:)
mliysmwgk

  • Chain 'G':
    Sequence, based on SEQRES records:
    >4n8vG (G:)
mhegvhrkpsllahpgplvkseetvilqcwsdvrfehfllhregkykdtlhligehhdgv
skanfsigpmmqdlagtyrcygsvthspyqlsapsdpldivitglyekpslsaqpgptvl
agesvtlscssrssydmyhlsregeaherrfsagpkvngtfqadfplgpathggtyrcfg
sfrdspyewsnssdpllvsvt

    Sequence, based on observed residues (ATOM records):
    >4n8vG (G:)
kpsllahpgplvkseetvilqcwsdvrfehfllhregkykdtlhligehskanfsigpmm
qdlagtyrcygsvthspyqlsapsdpldivitglyekpslsaqpgptvlagesvtlscss
rssydmyhlsregeaherrfsagpkvngtfqadfplgpathggtyrcfgsfrdspyewsn
ssdpllvsvt

  • Chain 'I':
    Sequence, based on SEQRES records:
    >4n8vI (I:)
mhegvhrkpsllahpgplvkseetvilqcwsdvrfehfllhregkykdtlhligehhdgv
skanfsigpmmqdlagtyrcygsvthspyqlsapsdpldivitglyekpslsaqpgptvl
agesvtlscssrssydmyhlsregeaherrfsagpkvngtfqadfplgpathggtyrcfg
sfrdspyewsnssdpllvsvt

    Sequence, based on observed residues (ATOM records):
    >4n8vI (I:)
kpsllahpgplvkseetvilqcwsdvrfehfllhregkykdtlhligehskanfsigpmm
qdlagtyrcygsvthspyqlsapsdpldivitglyekpslsaqpgptvlagesvtlscss
rssydmyhlsregeaherrfsagpkvngtfqadfplgpathggtyrcfgsfrdspyewsn
ssdpllvsvt