PDB entry 4n2c

View 4n2c on RCSB PDB site
Description: Crystal structure of Protein Arginine Deiminase 2 (F221/222A, 10 mM Ca2+)
Class: hydrolase
Keywords: deiminase, HYDROLASE
Deposited on 2013-10-04, released 2015-02-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-05-06, with a file datestamp of 2015-05-01.
Experiment type: XRAY
Resolution: 3.02 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein-arginine deiminase type-2
    Species: Homo sapiens [TaxId:9606]
    Gene: PADI2, KIAA0994, PDI2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y2J8 (Start-685)
      • engineered mutation (241-242)
    Domains in SCOPe 2.08: d4n2ca1, d4n2ca2, d4n2ca3
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4n2cA (A:)
mghhhhhhhhhhssghiegrhmlrertvrlqygsrveavyvlgtylwtdvysaapagaqt
fslkhsehvwvevvrdgeaeevatngkqrwllspsttlrvtmsqasteassdkvtvnyyd
eegsipidqaglfltaieisldvdadrdgvveknnpkkaswtwgpegqgaillvncdret
pwlpkedcrdekvyskedlkdmsqmilrtkgpdrlpagyeivlyismsdsdkvgvfyven
paagqryihilgrrklyhvvkytggsaellffveglcfpdegfsglvsihvslleymaqd
ipltpiftdtvifriapwimtpnilppvsvfvccmkdnylflkevknlvektncelkvcf
qylnrgdrwiqdeiefgyieaphkgfpvvldsprdgnlkdfpvkellgpdfgyvtreplf
esvtsldsfgnlevsppvtvngktyplgriligssfplsggrrmtkvvrdflkaqqvqap
velysdwltvghvdefmsfvpipgtkkflllmastsacyklfrekqkdghgeaimfkglg
gmsskritinkilsneslvqenlyfqrcldwnrdilkkelglteqdiidlpalfkmdedh
raraffpnmvnmivldkdlgipkpfgpqveeecclemhvrglleplglectfiddisayh
kflgevhcgtnvrrkpftfkwwhmvpsrrs

    Sequence, based on observed residues (ATOM records): (download) 
    >4n2cA (A:)
rertvrlqygsrveavyvlgtylwtdvysaapagaqtfslkhsehvwvevvrdgeaeeva
tngkqrwllspsttlrvtmsqasteassdkvtvnyydeegsipidqaglfltaieisldv
dadrdgvveknnpkkaswtwgpegqgaillvncdretpwlpkedcrdekvyskedlkdms
qmilrtkgpdrlpagyeivlyismsdsdkvgvfyvenpaagqryihilgrrklyhvvkyt
ggsaellffveglcfpdegfsglvsihvslleymaqdipltpiftdtvifriapwimtpn
ilppvsvfvccmkdtncelkvcfqylnrgdrwiqdeiefgyieaphkgfpvvldsprdgn
lkdfpvkellgpdfgyvtreplfesvtsldsfgnlevsppvtvngktyplgriligssfp
lsggrrmtkvvrdflkaqqvqapvelysdwltvghvdefmsfvpipgtkkflllmastsa
cyklfrekqkdghgeaimfkglggmsskritinkilsneslvqenlyfqrcldwnrdilk
kelglteqdiidlpalfkmdedhraraffpnmvnmivldkdlgipkpfgpqveeecclem
hvrglleplglectfiddhkflgevhcgtnvrrkpftfkwwhmvp