PDB entry 4mze

View 4mze on RCSB PDB site
Description: Crystal structure of hPIV3 hemagglutinin-neuraminidase, H552Q/Q559R mutant
Class: hydrolase
Keywords: viral envelope protein, viral fusion protein, HYDROLASE
Deposited on 2013-09-30, released 2013-11-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hemagglutinin-neuraminidase
    Species: Human parainfluenza 3 virus [TaxId:11217]
    Gene: HN
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08492 (Start-436)
      • engineered mutation (416)
      • engineered mutation (423)
    Domains in SCOPe 2.08: d4mzea_
  • Chain 'B':
    Compound: hemagglutinin-neuraminidase
    Species: Human parainfluenza 3 virus [TaxId:11217]
    Gene: HN
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08492 (Start-436)
      • engineered mutation (416)
      • engineered mutation (423)
    Domains in SCOPe 2.08: d4mzeb_
  • Heterogens: NAG, PO4, CA, EDO, PEG, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4mzeA (A:)
evppqrithdvgikplnpddfwrctsglpslmktpkirlmpgpgllampttvdgcvrtps
lvindliyaytsnlitrgcqdigksyqvlqigiitvnsdlvpdlnprishtfnindnrks
cslallntdvyqlcstpkvdersdyassgiedivldivnhdgsisttrfknnnisfdqpy
aalypsvgpgiyykgkiiflgygglehpinenaicnttgcpgktqrdcnqashspwfsdr
rmvnsiivvdkglnsipklkvwtismrqnywgsegrllllgnkiyiytrstswhsklqlg
iiditdysdirikwtwhnvlsrpgnnecpwghscpdgcitgvytdayplnptgsivssvi
ldsqksrvnpvityststervnelairnktlsagytttscithynkgycfhiveinqksl
dtfrpmlfkteipkscs

    Sequence, based on observed residues (ATOM records): (download) 
    >4mzeA (A:)
rithdvgikplnpddfwrctsglpslmktpkirlmpgpgllampttvdgcvrtpslvind
liyaytsnlitrgcqdigksyqvlqigiitvnsdlvpdlnprishtfnindnrkscslal
lntdvyqlcstpkvdersdyassgiedivldivnhdgsisttrfknnnisfdqpyaalyp
svgpgiyykgkiiflgygglehpinenaicnttgcpgktqrdcnqashspwfsdrrmvns
iivvdkglnsipklkvwtismrqnywgsegrllllgnkiyiytrstswhsklqlgiidit
dysdirikwtwhnvlsrpgnnecpwghscpdgcitgvytdayplnptgsivssvildsqk
srvnpvityststervnelairnktlsagytttscithynkgycfhiveinqksldtfrp
mlfkteipkscs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4mzeB (B:)
evppqrithdvgikplnpddfwrctsglpslmktpkirlmpgpgllampttvdgcvrtps
lvindliyaytsnlitrgcqdigksyqvlqigiitvnsdlvpdlnprishtfnindnrks
cslallntdvyqlcstpkvdersdyassgiedivldivnhdgsisttrfknnnisfdqpy
aalypsvgpgiyykgkiiflgygglehpinenaicnttgcpgktqrdcnqashspwfsdr
rmvnsiivvdkglnsipklkvwtismrqnywgsegrllllgnkiyiytrstswhsklqlg
iiditdysdirikwtwhnvlsrpgnnecpwghscpdgcitgvytdayplnptgsivssvi
ldsqksrvnpvityststervnelairnktlsagytttscithynkgycfhiveinqksl
dtfrpmlfkteipkscs

    Sequence, based on observed residues (ATOM records): (download) 
    >4mzeB (B:)
rithdvgikplnpddfwrctsglpslmktpkirlmpgpgllampttvdgcvrtpslvind
liyaytsnlitrgcqdigksyqvlqigiitvnsdlvpdlnprishtfnindnrkscslal
lntdvyqlcstpkvdersdyassgiedivldivnhdgsisttrfknnnisfdqpyaalyp
svgpgiyykgkiiflgygglehpinenaicnttgcpgktqrdcnqashspwfsdrrmvns
iivvdkglnsipklkvwtismrqnywgsegrllllgnkiyiytrstswhsklqlgiidit
dysdirikwtwhnvlsrpgnnecpwghscpdgcitgvytdayplnptgsivssvildsqk
srvnpvityststervnelairnktlsagytttscithynkgycfhiveinqksldtfrp
mlfkteipkscs