PDB entry 4mya

View 4mya on RCSB PDB site
Description: Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor A110
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: Structural Genomics, NIAID, National Institute of Allergy and Infectious Diseases, Center for Structural Genomics of Infectious Diseases, CSGID, TIM barrel, alpha-beta structure, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Deposited on 2013-09-27, released 2014-01-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Bacillus anthracis [TaxId:198094]
    Gene: guaB, BA_0008, BAS0011, GBAA_0008
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q81W29 (24-114)
      • expression tag (22-23)
      • linker (115)
    • Uniprot Q81W29 (117-End)
      • linker (116)
    Domains in SCOPe 2.08: d4myaa1, d4myaa2
  • Chain 'B':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Bacillus anthracis [TaxId:198094]
    Gene: guaB, BA_0008, BAS0011, GBAA_0008
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q81W29 (24-114)
      • expression tag (22-23)
      • linker (115)
    • Uniprot Q81W29 (117-End)
      • linker (116)
    Domains in SCOPe 2.08: d4myab1, d4myab2
  • Heterogens: IMP, 2EY, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4myaA (A:)
mhhhhhhssgvdlgtenlyfqsnamweskfvkegltfddvllvpaksdvlprevsvktvl
seslqlniplisagmdtvteadmaiamarqgglgiihknmsieqqaeqvdkvkrsggllv
gaavgvtadamtridalvkasvdaivldtahghsqgvidkvkevrakypslniiagnvat
aeatkalieaganvvkvgigpgsicttrvvagvgvpqltavydcatearkhgipviadgg
ikysgdmvkalaagahvvmlgsmfagvaespgeteiyqgrqfkvyrgmgsvgamekgskd
ryfqegnkklvpegiegrvpykgpladtvhqlvgglragmgycgaqdleflrenaqfirm
sgaglleshphhvqitkeapnysl

    Sequence, based on observed residues (ATOM records): (download) 
    >4myaA (A:)
namweskfvkegltfddvllvpaksdvlprevsvktvlseslqlniplisagmdtvtead
maiamarqgglgiihknmsieqqaeqvdkvkrsggllvgaavgvtadamtridalvkasv
daivldtahghsqgvidkvkevrakypslniiagnvataeatkalieaganvvkvgigpg
sicttrvvagvgvpqltavydcatearkhgipviadggikysgdmvkalaagahvvmlgs
mfagvaespgeteiyqgrqfkvyrgmgsvgamekkklvpegiegrvpykgpladtvhqlv
gglragmgycgaqdleflrenaqfirmsgaglleshphhvqitkeapny

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4myaB (B:)
mhhhhhhssgvdlgtenlyfqsnamweskfvkegltfddvllvpaksdvlprevsvktvl
seslqlniplisagmdtvteadmaiamarqgglgiihknmsieqqaeqvdkvkrsggllv
gaavgvtadamtridalvkasvdaivldtahghsqgvidkvkevrakypslniiagnvat
aeatkalieaganvvkvgigpgsicttrvvagvgvpqltavydcatearkhgipviadgg
ikysgdmvkalaagahvvmlgsmfagvaespgeteiyqgrqfkvyrgmgsvgamekgskd
ryfqegnkklvpegiegrvpykgpladtvhqlvgglragmgycgaqdleflrenaqfirm
sgaglleshphhvqitkeapnysl

    Sequence, based on observed residues (ATOM records): (download) 
    >4myaB (B:)
namweskfvkegltfddvllvpaksdvlprevsvktvlseslqlniplisagmdtvtead
maiamarqgglgiihknmsieqqaeqvdkvkrsggllvgaavgvtadamtridalvkasv
daivldtahghsqgvidkvkevrakypslniiagnvataeatkalieaganvvkvgigpg
sicttrvvagvgvpqltavydcatearkhgipviadggikysgdmvkalaagahvvmlgs
mfagvaespgeteiyqgrqfkvyrgmgsvgamekklvpegiegrvpykgpladtvhqlvg
glragmgycgaqdleflrenaqfirmsgaglleshphhvqitkeapny