PDB entry 4my6

View 4my6 on RCSB PDB site
Description: EnaH-EVH1 in complex with peptidomimetic low-molecular weight inhibitor Ac-[2-Cl-F]-[ProM-2]-[ProM-1]-OH
Class: Cell adhesion/inhibitor
Keywords: MOLECULAR RECOGNITION, ACTIN DYNAMICS, Cell adhesion-inhibitor complex
Deposited on 2013-09-27, released 2014-10-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-07-22, with a file datestamp of 2015-07-17.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein enabled homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: ENAH, MENA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4my6a_
  • Chain 'B':
    Compound: Protein enabled homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: ENAH, MENA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8N8S7 (2-112)
      • expression tag (1)
    Domains in SCOPe 2.08: d4my6b1, d4my6b2
  • Heterogens: 3VH, BR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4my6A (A:)
gsmseqsicqaraavmvyddankkwvpaggstgfsrvhiyhhtgnntfrvvgrkiqdhqv
vincaipkglkynqatqtfhqwrdarqvyglnfgskedanvfasammhalevl

    Sequence, based on observed residues (ATOM records): (download) 
    >4my6A (A:)
seqsicqaraavmvyddankkwvpaggstgfsrvhiyhhtgnntfrvvgrkiqdhqvvin
caipkglkynqatqtfhqwrdarqvyglnfgskedanvfasammhalevl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4my6B (B:)
gsmseqsicqaraavmvyddankkwvpaggstgfsrvhiyhhtgnntfrvvgrkiqdhqv
vincaipkglkynqatqtfhqwrdarqvyglnfgskedanvfasammhalevl

    Sequence, based on observed residues (ATOM records): (download) 
    >4my6B (B:)
smseqsicqaraavmvyddankkwvpaggstgfsrvhiyhhtgnntfrvvgrkiqdhqvv
incaipkglkynqatqtfhqwrdarqvyglnfgskedanvfasammhalevl