PDB entry 4mws

View 4mws on RCSB PDB site
Description: Crystal structure of human PPCA (trigonal crystal form 1)
Class: hydrolase
Keywords: cathepsin A, glycoprotein, serine protease, carboxypeptidase, protective protein, N-linked glycosylation, proteolytically activated form, lysosomal enzyme, HYDROLASE
Deposited on 2013-09-25, released 2014-03-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: lysosomal protective protein
    Species: Homo sapiens [TaxId:9606]
    Gene: CTSA, PPGB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4mwsa_
  • Chain 'B':
    Compound: lysosomal protective protein
    Species: Homo sapiens [TaxId:9606]
    Gene: CTSA, PPGB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4mwsb_
  • Heterogens: NAG, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4mwsA (A:)
apdqdeiqrlpglakqpsfrqysgylkgsgskhlhywfvesqkdpenspvvlwlnggpgc
ssldglltehgpflvqpdgvtleynpyswnlianvlylespagvgfsysddkfyatndte
vaqsnfealqdffrlfpeyknnklfltgesyagiyiptlavlvmqdpsmnlqglavgngl
ssyeqndnslvyfayyhgllgnrlwsslqthccsqnkcnfydnkdlecvtnlqevarivg
nsglniynlyapcaggvpshfrsgdkvrmdppctnttaastylnnpyvrkalnipeqlpq
wdmcnflvnlqyrrlyrsmnsqylkllssqkyqillyngdvdmacnfmgdewfvdslnqk
mevqrrpwlvkygdsgeqiagfvkefshiafltikgaghmvptdkplaaftmfsrflnkq
pyhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4mwsA (A:)
apdqdeiqrlpglakqpsfrqysgylkgsgskhlhywfvesqkdpenspvvlwlnggpgc
ssldglltehgpflvqpdgvtleynpyswnlianvlylespagvgfsysddkfyatndte
vaqsnfealqdffrlfpeyknnklfltgesyagiyiptlavlvmqdpsmnlqglavgngl
ssyeqndnslvyfayyhgllgnrlwsslqthccsqnkcnfydnkdlecvtnlqevarivg
nsglniynlyapcaggvprmdppctnttaastylnnpyvrkalnipeqlpqwdmcnflvn
lqyrrlyrsmnsqylkllssqkyqillyngdvdmacnfmgdewfvdslnqkmevqrrpwl
vkygdsgeqiagfvkefshiafltikgaghmvptdkplaaftmfsrflnkqpy

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4mwsB (B:)
apdqdeiqrlpglakqpsfrqysgylkgsgskhlhywfvesqkdpenspvvlwlnggpgc
ssldglltehgpflvqpdgvtleynpyswnlianvlylespagvgfsysddkfyatndte
vaqsnfealqdffrlfpeyknnklfltgesyagiyiptlavlvmqdpsmnlqglavgngl
ssyeqndnslvyfayyhgllgnrlwsslqthccsqnkcnfydnkdlecvtnlqevarivg
nsglniynlyapcaggvpshfrsgdkvrmdppctnttaastylnnpyvrkalnipeqlpq
wdmcnflvnlqyrrlyrsmnsqylkllssqkyqillyngdvdmacnfmgdewfvdslnqk
mevqrrpwlvkygdsgeqiagfvkefshiafltikgaghmvptdkplaaftmfsrflnkq
pyhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4mwsB (B:)
apdqdeiqrlpglakqpsfrqysgylkgsgskhlhywfvesqkdpenspvvlwlnggpgc
ssldglltehgpflvqpdgvtleynpyswnlianvlylespagvgfsysddkfyatndte
vaqsnfealqdffrlfpeyknnklfltgesyagiyiptlavlvmqdpsmnlqglavgngl
ssyeqndnslvyfayyhgllgnrlwsslqthccsqnkcnfydnkdlecvtnlqevarivg
nsglniynlyapcaggvprmdppctnttaastylnnpyvrkalnipeqlpqwdmcnflvn
lqyrrlyrsmnsqylkllssqkyqillyngdvdmacnfmgdewfvdslnqkmevqrrpwl
vkygdsgeqiagfvkefshiafltikgaghmvptdkplaaftmfsrflnkqpy