PDB entry 4mwi

View 4mwi on RCSB PDB site
Description: Crystal structure of the human MLKL pseudokinase domain
Class: transferase
Keywords: Pseudokinase, necroptosis, transferase
Deposited on 2013-09-25, released 2013-12-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-04-16, with a file datestamp of 2014-04-11.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.166
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: mixed lineage kinase domain-like protein
    Species: Homo sapiens [TaxId:9606]
    Gene: Mlkl
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4mwia_
  • Heterogens: PXN, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4mwiA (A:)
gamgskcmqeipqeqikeikkeqlsgspwillrenevstlykgeyhrapvaikvfkklqa
gsiaivrqtfnkeiktmkkfespnilrifgicidetvtppqfsivmeycelgtlrelldr
ekdltlgkrmvlvlgaarglyrlhhseapelhgkirssnflvtqgyqvklagfelrktqt
smslgttrektdrvkstaylspqeledvfyqydvkseiysfgivlweiatgdipfqgcns
ekirklvavkrqqeplgedcpselreiidecrahdpsvrpsvdeilkklstfsk

    Sequence, based on observed residues (ATOM records): (download) 
    >4mwiA (A:)
ikeikkeqlsgspwillrenevstlykgeyhrapvaikvfkklqagsiaivrqtfnkeik
tmkkfespnilrifgicidetvtppqfsivmeycelgtlrelldrekdltlgkrmvlvlg
aarglyrlhhseapelhgkirssnflvtqgyqvklagfelrktqdrvkstaylspqeled
vfyqydvkseiysfgivlweiatgdipfqgcnsekirklvavkrqqeplgedcpselrei
idecrahdpsvrpsvdeilkklstfs