PDB entry 4muz

View 4muz on RCSB PDB site
Description: Crystal structure of orotidine 5'-monophosphate decarboxylase from Archaeoglobus fulgidus complexed with inhibitor BMP
Class: lyase/lyase inhibitor
Keywords: TIM barrel, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE, INHIBITOR BMP, LYASE-LYASE INHIBITOR complex
Deposited on 2013-09-23, released 2013-10-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-10-16, with a file datestamp of 2013-10-11.
Experiment type: XRAY
Resolution: 1.39 Å
R-factor: 0.162
AEROSPACI score: 0.71 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: orotidine 5'-phosphate decarboxylase
    Species: Archaeoglobus fulgidus [TaxId:2234]
    Gene: pyrF, AF_0929
    Database cross-references and differences (RAF-indexed):
    • Uniprot O29333 (20-228)
      • expression tag (17-19)
    Domains in SCOPe 2.08: d4muza1, d4muza2
  • Chain 'B':
    Compound: orotidine 5'-phosphate decarboxylase
    Species: Archaeoglobus fulgidus [TaxId:2234]
    Gene: pyrF, AF_0929
    Database cross-references and differences (RAF-indexed):
    • Uniprot O29333 (20-228)
      • expression tag (17-19)
    Domains in SCOPe 2.08: d4muzb1, d4muzb2
  • Heterogens: BMP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4muzA (A:)
mgsshhhhhhssglvprgshmkqlilaldvmdgekameiakkvaehvdrikvnyplvlsa
gvgimkrlseikpviadfkiadvpytssliariafensaesvivhgfvgsdtlrevcrva
eefggkvyavtelsspggeefmsavslkivekakeagchgliapstrierlreirkaagd
meilcpgigaqkgsieavkyadgiivgrgiyasgnpaeearklrrvlki

    Sequence, based on observed residues (ATOM records): (download) 
    >4muzA (A:)
gshmkqlilaldvmdgekameiakkvaehvdrikvnyplvlsagvgimkrlseikpviad
fkiadvpytssliariafensaesvivhgfvgsdtlrevcrvaeefggkvyavtelsspg
geefmsavslkivekakeagchgliapstrierlreirkaagdmeilcpgigaqkgsiea
vkyadgiivgrgiyasgnpaeearklrrvlki

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4muzB (B:)
mgsshhhhhhssglvprgshmkqlilaldvmdgekameiakkvaehvdrikvnyplvlsa
gvgimkrlseikpviadfkiadvpytssliariafensaesvivhgfvgsdtlrevcrva
eefggkvyavtelsspggeefmsavslkivekakeagchgliapstrierlreirkaagd
meilcpgigaqkgsieavkyadgiivgrgiyasgnpaeearklrrvlki

    Sequence, based on observed residues (ATOM records): (download) 
    >4muzB (B:)
gshmkqlilaldvmdgekameiakkvaehvdrikvnyplvlsagvgimkrlseikpviad
fkiadvpytssliariafensaesvivhgfvgsdtlrevcrvaeefggkvyavtelsspg
geefmsavslkivekakeagchgliapstrierlreirkaagdmeilcpgigaqkgsiea
vkyadgiivgrgiyasgnpaeearklrrvlki