PDB entry 4mus

View 4mus on RCSB PDB site
Description: Crystal structure of vancomycin resistance D,D-dipeptidase/D,D-pentapeptidase VanXYc D59S mutant in complex with D-Ala-D-Ala phosphinate analog
Deposited on 2013-09-23, released 2013-10-09
The last revision was dated 2014-05-14, with a file datestamp of 2014-05-09.
Experiment type: XRAY
Resolution: 1.68 Å
R-factor: 0.17
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: D,D-dipeptidase/D,D-carboxypeptidase
    Species: Enterococcus gallinarum [TaxId:1353]
    Gene: vanXYc
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JN36 (21-End)
      • engineered mutation (79)
  • Chain 'B':
    Compound: D,D-dipeptidase/D,D-carboxypeptidase
    Species: Enterococcus gallinarum [TaxId:1353]
    Gene: vanXYc
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9JN36 (21-End)
      • engineered mutation (79)
  • Heterogens: ZN, 2D8, LY0, SO4, GOL, CL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4musA (A:)
mgsshhhhhhssgrenlyfqgmntlqlinknhplkknqepphlvlapfsdhdvylqpeva
kqwerlvratglekdirlvsgyrtekeqrrlweyslkenglaytkqfvalpgcsehqigl
aidvglkkqedddlicphfrdsaaadlfmqqmmnygfilrypedkqeitgisyepwhfry
vglphsqvitaqkwtleeyhdylaqtvrqfa

    Sequence, based on observed residues (ATOM records):
    >4musA (A:)
mntlqlinknhplkknqepphlvlapfsdhdvylqpevakqwerlvratglekdirlvsg
yrtekeqrrlweyslkenglaytkqfvalpgcsehqiglaidvglkkqedddlicphfrd
saaadlfmqqmmnygfilrypedkqeitgisyepwhfryvglphsqvitaqkwtleeyhd
ylaqtvrq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4musB (B:)
mgsshhhhhhssgrenlyfqgmntlqlinknhplkknqepphlvlapfsdhdvylqpeva
kqwerlvratglekdirlvsgyrtekeqrrlweyslkenglaytkqfvalpgcsehqigl
aidvglkkqedddlicphfrdsaaadlfmqqmmnygfilrypedkqeitgisyepwhfry
vglphsqvitaqkwtleeyhdylaqtvrqfa

    Sequence, based on observed residues (ATOM records):
    >4musB (B:)
mntlqlinknhplkknqepphlvlapfsdhdvylqpevakqwerlvratglekdirlvsg
yrtekeqrrlweyslkenglaytkqfvalpgcsehqiglaidvglkkqedddlicphfrd
saaadlfmqqmmnygfilrypedkqeitgisyepwhfryvglphsqvitaqkwtleeyhd
ylaqtvrq