PDB entry 4msv

View 4msv on RCSB PDB site
Description: Crystal structure of FASL and DcR3 complex
Class: immune system
Keywords: FASL, DCR3, TNF, TNFR, TNF6, STRUCTURAL GENOMICS, PSI-BIOLOGY, NEW YORK STRUCTURAL GENOMICS, RESEARCH CONSORTIUM, NYSGRC, IMMUNITY, TNF SUPE CD95L, FAS LIGAND, MEMBRANE, ATOMS-TO-ANIMALS: THE IMMUNE FUNCTION NETWORK, IFN, JELLY-ROLL FOLD, BIND TNF RECEPTOR FAS, Protein Structure Initiative, New York Structural Genomics Research Consortium, CD95L, TNF SUPERFAMILY, SECRETED PROTEIN, CYTOKINE, IMMUNE SYSTEM
Deposited on 2013-09-18, released 2013-11-27
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-03-26, with a file datestamp of 2014-03-21.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.189
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Tumor necrosis factor ligand superfamily member 6
  Species: Homo sapiens [TaxId:9606]
  Gene: FASLG, APT1LG1, CD95L, FASL, TNFSF6
  Database cross-references and differences (RAF-indexed):
  • Uniprot P48023 (Start-151)
  Domains in SCOPe 2.05: d4msva_
• Chain 'B':
  Compound: Tumor necrosis factor receptor superfamily member 6B
  Species: Homo sapiens [TaxId:9606]
  Gene: TNFRSF6B, DCR3, TR6, UNQ186/PRO212
  Database cross-references and differences (RAF-indexed):
  • Uniprot O95407
• Heterogens: MG, GOL, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >4msvA (A:)
  qighpspppekkelrkvahltgksnsrsmplewedtygivllsgvkykkgglvinetgly
  fvyskvyfrgqscnnlplshkvymrnskypqdlvmmegkmmsycttgqmwarssylgavf
  nltsadhlyvnvselslvnfeesqtffglykl
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >4msvA (A:)
  lrkvahltgksnsrsmplewedtygivllsgvkykkgglvinetglyfvyskvyfrgqsc
  nnlplshkvymrnskypqdlvmmegkmmsycttgqmwarssylgavfnltsadhlyvnvs
  elslvnfeesqtffglykl
  

  
  
• Chain 'B':
  No sequence available.