PDB entry 4msu

View 4msu on RCSB PDB site
Description: Human GKRP bound to AMG-6861 and Sorbitol-6-phosphate
Deposited on 2013-09-18, released 2014-03-12
The last revision was dated 2014-03-12, with a file datestamp of 2014-03-07.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.215
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glucokinase regulatory protein
    Species: Homo sapiens [TaxId:9606]
    Gene: gckr
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: glucokinase regulatory protein
    Species: Homo sapiens [TaxId:9606]
    Gene: gckr
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 2EU, S6P, IOD, GOL, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4msuA (A:)
mhhhhhhdevdmpgtkrfqhvietpepgkwelsgyeaavpiteksnpltqdldkadaeni
vrllgqcdaeifqeegqalstyqrlysesilttmvqvagkvqevlkepdgglvvlsgggt
sgrmaflmsvsfnqlmkglgqkplytyliaggdrsvvasregtedsalhgieelkkvaag
kkrvivigisvglsapfvagqmdccmnntavflpvlvgfnpvsmarndpiedwsstfrqv
aermqkmqekqkafvlnpaigpeglsgssrmkggsatkilletlllaahktvdqgiaasq
rclleilrtferahqvtysqspkiatlmksvstslekkghvylvgwqtlgiiaimdgvec
ihtfgadfrdvrgfligdhsdmfnqkaeltnqgpqftfsqedfltsilpslteidtvvfi
ftlddnltevqtiveqvkektnhiqalahstvgqtlpiplkklfpsiisitwpllffeye
gnfiqkfqrelstkwvlntvstgahvllgkilqnhmldlrisnsklfwralamlqrfsgq
skarciesllraihfpqplsddiraapischvqvahekeqvipiallsllfrcsiteaqa
hlaaapsvceavrsalagpgqkrtadpleilepdvq

    Sequence, based on observed residues (ATOM records):
    >4msuA (A:)
mpgtkrfqhvietpepgkwelsgyeaavpiteksnpltqdldkadaenivrllgqcdaei
fqeegqstyqrlysesilttmvqvagkvqevlkepdgglvvlsgggtsgrmaflmsvsfn
qlmkglgqkplytyliaggdrsvvasregtedsalhgieelkkvaagkkrvivigisvgl
sapfvagqmdccmnntavflpvlvgfnpvsmarndpiedwsstfrqvaermqkmqekqka
fvlnpaigpeglsgssrmkggsatkilletlllaahktvdqgiaasqrclleilrtfera
hqvtysqspkiatlmksvstslekkghvylvgwqtlgiiaimdgvecihtfgadfrdvrg
fliftfsqedfltsilpslteidtvvfiftlddnltevqtiveqvkektnhiqalahstv
gqtlpiplkklfpsiisitwpllffeyegnfiqkfqrelstkwvlntvstgahvllgkil
qnhmldlrisnsklfwralamlqrfsgqskarciesllraihfpqplsddiraapischv
qvahekeqvipiallsllfrcsiteaqahlaaapsvceavrsala

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4msuB (B:)
mhhhhhhdevdmpgtkrfqhvietpepgkwelsgyeaavpiteksnpltqdldkadaeni
vrllgqcdaeifqeegqalstyqrlysesilttmvqvagkvqevlkepdgglvvlsgggt
sgrmaflmsvsfnqlmkglgqkplytyliaggdrsvvasregtedsalhgieelkkvaag
kkrvivigisvglsapfvagqmdccmnntavflpvlvgfnpvsmarndpiedwsstfrqv
aermqkmqekqkafvlnpaigpeglsgssrmkggsatkilletlllaahktvdqgiaasq
rclleilrtferahqvtysqspkiatlmksvstslekkghvylvgwqtlgiiaimdgvec
ihtfgadfrdvrgfligdhsdmfnqkaeltnqgpqftfsqedfltsilpslteidtvvfi
ftlddnltevqtiveqvkektnhiqalahstvgqtlpiplkklfpsiisitwpllffeye
gnfiqkfqrelstkwvlntvstgahvllgkilqnhmldlrisnsklfwralamlqrfsgq
skarciesllraihfpqplsddiraapischvqvahekeqvipiallsllfrcsiteaqa
hlaaapsvceavrsalagpgqkrtadpleilepdvq

    Sequence, based on observed residues (ATOM records):
    >4msuB (B:)
mpgtkrfqhvietpepgkwelsgyeaavpiteksnpltqdldkadaenivrllgqcdaei
fqeegqstyqrlysesilttmvqvagkvqevlkepdgglvvlsgggtsgrmaflmsvsfn
qlmkglgqkplytyliaggdrsvvasregtedsalhgieelkkvaagkkrvivigisvgl
sapfvagqmdccmnntavflpvlvgfnpvsmarndpiedwsstfrqvaermqkmqekqka
fvlnpaigpeglsgssrmkggsatkilletlllaahktvdqgiaasqrclleilrtfera
hqvtysqspkiatlmksvstslekkghvylvgwqtlgiiaimdgvecihtfgadfrdvrg
fligqgpqftfsqedfltsilpslteidtvvfiftlddnltevqtiveqvkektnhiqal
ahstvgqtlpiplkklfpsiisitwpllffeyegnfiqkfqrelstkwvlntvstgahvl
lgkilqnhmldlrisnsklfwralamlqrfsgqskarciesllraihfpqplsddiraap
ischvqvahekeqvipiallsllfrcsiteaqahlaaapsvceavrsala