PDB entry 4msq

View 4msq on RCSB PDB site
Description: Crystal structure of Schizosaccharomyces pombe AMSH-like protease sst2 catalytic domain bound to ubiquitin
Class: hydrolase/protein binding
Keywords: ubiquitin, deubiquitination, Helix-beta-helix sandwich, Zinc metalloprotease, lysine 63-linked polyubiquitin, cytosol, endosome, HYDROLASE-PROTEIN BINDING complex
Deposited on 2013-09-18, released 2014-06-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-06-18, with a file datestamp of 2014-06-13.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.177
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: AMSH-like protease sst2
    Species: Schizosaccharomyces pombe [TaxId:284812]
    Gene: sst2, SPAC19B12.10
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC, Ubiquitin
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0CG48 (5-80)
      • expression tag (4)
    Domains in SCOPe 2.07: d4msqb1, d4msqb2
  • Chain 'C':
    Compound: AMSH-like protease sst2
    Species: Schizosaccharomyces pombe [TaxId:284812]
    Gene: sst2, SPAC19B12.10
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC, Ubiquitin
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4msqd_
  • Heterogens: ZN, EDO, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4msqB (B:)
    gplgsmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrt
    lsdyniqkestlhlvlrlrgg
    

    Sequence, based on observed residues (ATOM records): (download)
    >4msqB (B:)
    smqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdy
    niqkestlhlvlrlrgg
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >4msqD (D:)
    gplgsmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrt
    lsdyniqkestlhlvlrlrgg
    

    Sequence, based on observed residues (ATOM records): (download)
    >4msqD (D:)
    qifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyni
    qkestlhlvlrlrgg