PDB entry 4ms4

View 4ms4 on RCSB PDB site
Description: crystal structure of the extracellular domain of human gaba(b) receptor bound to the agonist baclofen
Deposited on 2013-09-18, released 2013-12-11
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Gamma-aminobutyric acid type B receptor subunit 1
    Species: Homo sapiens [TaxId:9606]
    Gene: GABBR1, GPRC3A
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UBS5 (Start-411)
      • expression tag (412-417)
  • Chain 'B':
    Compound: Gamma-aminobutyric acid type B receptor subunit 2
    Species: Homo sapiens [TaxId:9606]
    Gene: GABBR2, GPR51, GPRC3B
    Database cross-references and differences (RAF-indexed):
    • Uniprot O75899 (Start-424)
      • expression tag (425)
  • Heterogens: 2C0, NAG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4ms4A (A:)
serravyigalfpmsggwpggqacqpavemaledvnsrrdilpdyelklihhdskcdpgq
atkylyellyndpikiilmpgcssvstlvaeaarmwnlivlsygssspalsnrqrfptff
rthpsatlhnptrvklfekwgwkkiatiqqttevftstlddleervkeagieitfrqsff
sdpavpvknlkrqdariivglfyetearkvfcevykerlfgkkyvwfligwyadnwfkiy
dpsinctvdemteaveghitteivmlnpantrsisnmtsqefvekltkrlkrhpeetggf
qeaplaydaiwalalalnktsggggrsgvrledfnynnqtitdqiyramnsssfegvsgh
vvfdasgsrmawtlieqlqggsykkigyydstkddlswsktdkwiggsppaddykddddk

    Sequence, based on observed residues (ATOM records):
    >4ms4A (A:)
rravyigalfpmsggwpggqacqpavemaledvnsrrdilpdyelklihhdskcdpgqat
kylyellyndpikiilmpgcssvstlvaeaarmwnlivlsygssspalsnrqrfptffrt
hpsatlhnptrvklfekwgwkkiatiqqttevftstlddleervkeagieitfrqsffsd
pavpvknlkrqdariivglfyetearkvfcevykerlfgkkyvwfligwyadnwfkiydp
sinctvdemteaveghitteivmlnpantrsisnmtsqefvekltkrlkrhpeetggfqe
aplaydaiwalalalnktsrledfnynnqtitdqiyramnsssfegvsghvvfdasgsrm
awtlieqlqggsykkigyydstkddlswsktdkwiggsppaddykddd

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4ms4B (B:)
wargaprpppsspplsimglmpltkevakgsigrgvlpavelaieqirnesllrpyfldl
rlydtecdnakglkafydaikygpnhlmvfggvcpsvtsiiaeslqgwnlvqlsfaattp
vladkkkypyffrtvpsdnavnpailkllkhyqwkrvgtltqdvqrfsevrndltgvlyg
edieisdtesfsndpctsvkklkgndvriilgqfdqnmaakvfccayeenmygskyqwii
pgwyepswweqvhteanssrclrknllaamegyigvdfeplsskqiktisgktpqqyere
ynnkrsgvgpskfhgyaydgiwviaktlqrametlhassrhqriqdfnytdhtlgriiln
amnetnffgvtgqvvfrngermgtikftqfqdsrevkvgeynavadtleiindtirfqgs
eppkddykddddk

    Sequence, based on observed residues (ATOM records):
    >4ms4B (B:)
ppsspplsimglmpltkevakgsigrgvlpavelaieqirnesllrpyfldlrlydtecd
nakglkafydaikygpnhlmvfggvcpsvtsiiaeslqgwnlvqlsfaattpvladkkky
pyffrtvpsdnavnpailkllkhyqwkrvgtltqdvqrfsevrndltgvlygedieisdt
esfsndpctsvkklkgndvriilgqfdqnmaakvfccayeenmygskyqwiipgwyepsw
weclrknllaamegyigvdfeplsskqiktisgktpqqyereynnkrsgvgpskfhgyay
dgiwviaktlqrametlhassrhqriqdfnytdhtlgriilnamnetnffgvtgqvvfrn
germgtikftqfqdsrevkvgeynavadtleiindtirfqgseppkdd