PDB entry 4miv

View 4miv on RCSB PDB site
Description: crystal structure of sulfamidase, crystal form l
Deposited on 2013-09-02, released 2014-05-14
The last revision was dated 2021-06-02, with a file datestamp of 2021-05-28.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: N-sulphoglucosamine sulphohydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: SGSH, HSS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51688 (Start-501)
      • modified residue (69)
      • expression tag (502-504)
  • Chain 'B':
    Compound: N-sulphoglucosamine sulphohydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: SGSH, HSS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51688 (Start-501)
      • modified residue (69)
  • Chain 'C':
    Compound: N-sulphoglucosamine sulphohydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: SGSH, HSS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51688 (Start-501)
      • modified residue (69)
      • expression tag (502-503)
  • Chain 'D':
    Compound: N-sulphoglucosamine sulphohydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: SGSH, HSS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51688
      • modified residue (69)
  • Chain 'E':
    Compound: N-sulphoglucosamine sulphohydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: SGSH, HSS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51688 (Start-501)
      • modified residue (69)
      • expression tag (502-503)
  • Chain 'F':
    Compound: N-sulphoglucosamine sulphohydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: SGSH, HSS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51688
      • modified residue (69)
  • Chain 'G':
    Compound: N-sulphoglucosamine sulphohydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: SGSH, HSS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51688
      • modified residue (69)
  • Chain 'H':
    Compound: N-sulphoglucosamine sulphohydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: SGSH, HSS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51688 (Start-501)
      • modified residue (69)
      • expression tag (502)
  • Heterogens: CA, NAG, CL, PEG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4mivA (A:)
mscpvpaccalllvlglcrarprnalllladdggfesgaynnsaiatphldalarrsllf
rnaftsvsssspsraslltglpqhqngmyglhqdvhhfnsfdkvrslplllsqagvrtgi
igkkhvgpetvypfdfayteengsvlqvgrnitrikllvrkflqtqddrpfflyvafhdp
hrcghsqpqygtfcekfgngesgmgripdwtpqaydpldvlvpyfvpntpaaradlaaqy
ttvgrmdqgvglvlqelrdagvlndtlviftsdngipfpsgrtnlywpgtaepllvsspe
hpkrwgqvseayvslldltptildwfsipypsyaifgsktihltgrsllpaleaeplwat
vfgsqshhevtmsypmrsvqhrhfrlvhnlnfkmpfpidqdfyvsptfqdllnrttagqp
tgwykdlrhyyyrarwelydrsrdphetqnlatdprfaqllemlrdqlakwqwethdpwv
capdgvleeklspqcqplhnelrshhhhhh

    Sequence, based on observed residues (ATOM records):
    >4mivA (A:)
prnalllladdggfesgaynnsaiatphldalarrsllfrnaftsvsssspsraslltgl
pqhqngmyglhqdvhhfnsfdkvrslplllsqagvrtgiigkkhvgpetvypfdfaytee
ngsvlqvgrnitrikllvrkflqtqddrpfflyvafhdphrcghsqpqygtfcekfgnge
sgmgripdwtpqaydpldvlvpyfvpntpaaradlaaqyttvgrmdqgvglvlqelrdag
vlndtlviftsdngipfpsgrtnlywpgtaepllvsspehpkrwgqvseayvslldltpt
ildwfsipypsyaifgsktihltgrsllpaleaeplwatvfgsqshhevtmsypmrsvqh
rhfrlvhnlnfkmpfpidqdfyvsptfqdllnrttagqptgwykdlrhyyyrarwelydr
srdphetqnlatdprfaqllemlrdqlakwqwethdpwvcapdgvleeklspqcqplhne
lrsh

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4mivB (B:)
mscpvpaccalllvlglcrarprnalllladdggfesgaynnsaiatphldalarrsllf
rnaftsvsssspsraslltglpqhqngmyglhqdvhhfnsfdkvrslplllsqagvrtgi
igkkhvgpetvypfdfayteengsvlqvgrnitrikllvrkflqtqddrpfflyvafhdp
hrcghsqpqygtfcekfgngesgmgripdwtpqaydpldvlvpyfvpntpaaradlaaqy
ttvgrmdqgvglvlqelrdagvlndtlviftsdngipfpsgrtnlywpgtaepllvsspe
hpkrwgqvseayvslldltptildwfsipypsyaifgsktihltgrsllpaleaeplwat
vfgsqshhevtmsypmrsvqhrhfrlvhnlnfkmpfpidqdfyvsptfqdllnrttagqp
tgwykdlrhyyyrarwelydrsrdphetqnlatdprfaqllemlrdqlakwqwethdpwv
capdgvleeklspqcqplhnelrshhhhhh

    Sequence, based on observed residues (ATOM records):
    >4mivB (B:)
prnalllladdggfesgaynnsaiatphldalarrsllfrnaftsvsssspsraslltgl
pqhqngmyglhqdvhhfnsfdkvrslplllsqagvrtgiigkkhvgpetvypfdfaytee
ngsvlqvgrnitrikllvrkflqtqddrpfflyvafhdphrcghsqpqygtfcekfgnge
sgmgripdwtpqaydpldvlvpyfvpntpaaradlaaqyttvgrmdqgvglvlqelrdag
vlndtlviftsdngipfpsgrtnlywpgtaepllvsspehpkrwgqvseayvslldltpt
ildwfsipypsyaifgsktihltgrsllpaleaeplwatvfgsqshhevtmsypmrsvqh
rhfrlvhnlnfkmpfpidqdfyvsptfqdllnrttagqptgwykdlrhyyyrarwelydr
srdphetqnlatdprfaqllemlrdqlakwqwethdpwvcapdgvleeklspqcqplhne
l

  • Chain 'C':
    Sequence, based on SEQRES records:
    >4mivC (C:)
mscpvpaccalllvlglcrarprnalllladdggfesgaynnsaiatphldalarrsllf
rnaftsvsssspsraslltglpqhqngmyglhqdvhhfnsfdkvrslplllsqagvrtgi
igkkhvgpetvypfdfayteengsvlqvgrnitrikllvrkflqtqddrpfflyvafhdp
hrcghsqpqygtfcekfgngesgmgripdwtpqaydpldvlvpyfvpntpaaradlaaqy
ttvgrmdqgvglvlqelrdagvlndtlviftsdngipfpsgrtnlywpgtaepllvsspe
hpkrwgqvseayvslldltptildwfsipypsyaifgsktihltgrsllpaleaeplwat
vfgsqshhevtmsypmrsvqhrhfrlvhnlnfkmpfpidqdfyvsptfqdllnrttagqp
tgwykdlrhyyyrarwelydrsrdphetqnlatdprfaqllemlrdqlakwqwethdpwv
capdgvleeklspqcqplhnelrshhhhhh

    Sequence, based on observed residues (ATOM records):
    >4mivC (C:)
rprnalllladdggfesgaynnsaiatphldalarrsllfrnaftsvsssspsraslltg
lpqhqngmyglhqdvhhfnsfdkvrslplllsqagvrtgiigkkhvgpetvypfdfayte
engsvlqvgrnitrikllvrkflqtqddrpfflyvafhdphrcghsqpqygtfcekfgng
esgmgripdwtpqaydpldvlvpyfvpntpaaradlaaqyttvgrmdqgvglvlqelrda
gvlndtlviftsdngipfpsgrtnlywpgtaepllvsspehpkrwgqvseayvslldltp
tildwfsipypsyaifgsktihltgrsllpaleaeplwatvfgsqshhevtmsypmrsvq
hrhfrlvhnlnfkmpfpidqdfyvsptfqdllnrttagqptgwykdlrhyyyrarwelyd
rsrdphetqnlatdprfaqllemlrdqlakwqwethdpwvcapdgvleeklspqcqplhn
elrs

  • Chain 'D':
    Sequence, based on SEQRES records:
    >4mivD (D:)
mscpvpaccalllvlglcrarprnalllladdggfesgaynnsaiatphldalarrsllf
rnaftsvsssspsraslltglpqhqngmyglhqdvhhfnsfdkvrslplllsqagvrtgi
igkkhvgpetvypfdfayteengsvlqvgrnitrikllvrkflqtqddrpfflyvafhdp
hrcghsqpqygtfcekfgngesgmgripdwtpqaydpldvlvpyfvpntpaaradlaaqy
ttvgrmdqgvglvlqelrdagvlndtlviftsdngipfpsgrtnlywpgtaepllvsspe
hpkrwgqvseayvslldltptildwfsipypsyaifgsktihltgrsllpaleaeplwat
vfgsqshhevtmsypmrsvqhrhfrlvhnlnfkmpfpidqdfyvsptfqdllnrttagqp
tgwykdlrhyyyrarwelydrsrdphetqnlatdprfaqllemlrdqlakwqwethdpwv
capdgvleeklspqcqplhnelrshhhhhh

    Sequence, based on observed residues (ATOM records):
    >4mivD (D:)
prnalllladdggfesgaynnsaiatphldalarrsllfrnaftsvsssspsraslltgl
pqhqngmyglhqdvhhfnsfdkvrslplllsqagvrtgiigkkhvgpetvypfdfaytee
ngsvlqvgrnitrikllvrkflqtqddrpfflyvafhdphrcghsqpqygtfcekfgnge
sgmgripdwtpqaydpldvlvpyfvpntpaaradlaaqyttvgrmdqgvglvlqelrdag
vlndtlviftsdngipfpsgrtnlywpgtaepllvsspehpkrwgqvseayvslldltpt
ildwfsipypsyaifgsktihltgrsllpaleaeplwatvfgsqshhevtmsypmrsvqh
rhfrlvhnlnfkmpfpidqdfyvsptfqdllnrttagqptgwykdlrhyyyrarwelydr
srdphetqnlatdprfaqllemlrdqlakwqwethdpwvcapdgvleeklspqcqplhne

  • Chain 'E':
    Sequence, based on SEQRES records:
    >4mivE (E:)
mscpvpaccalllvlglcrarprnalllladdggfesgaynnsaiatphldalarrsllf
rnaftsvsssspsraslltglpqhqngmyglhqdvhhfnsfdkvrslplllsqagvrtgi
igkkhvgpetvypfdfayteengsvlqvgrnitrikllvrkflqtqddrpfflyvafhdp
hrcghsqpqygtfcekfgngesgmgripdwtpqaydpldvlvpyfvpntpaaradlaaqy
ttvgrmdqgvglvlqelrdagvlndtlviftsdngipfpsgrtnlywpgtaepllvsspe
hpkrwgqvseayvslldltptildwfsipypsyaifgsktihltgrsllpaleaeplwat
vfgsqshhevtmsypmrsvqhrhfrlvhnlnfkmpfpidqdfyvsptfqdllnrttagqp
tgwykdlrhyyyrarwelydrsrdphetqnlatdprfaqllemlrdqlakwqwethdpwv
capdgvleeklspqcqplhnelrshhhhhh

    Sequence, based on observed residues (ATOM records):
    >4mivE (E:)
prnalllladdggfesgaynnsaiatphldalarrsllfrnaftsvsssspsraslltgl
pqhqngmyglhqdvhhfnsfdkvrslplllsqagvrtgiigkkhvgpetvypfdfaytee
ngsvlqvgrnitrikllvrkflqtqddrpfflyvafhdphrcghsqpqygtfcekfgnge
sgmgripdwtpqaydpldvlvpyfvpntpaaradlaaqyttvgrmdqgvglvlqelrdag
vlndtlviftsdngipfpsgrtnlywpgtaepllvsspehpkrwgqvseayvslldltpt
ildwfsipypsyaifgsktihltgrsllpaleaeplwatvfgsqshhevtmsypmrsvqh
rhfrlvhnlnfkmpfpidqdfyvsptfqdllnrttagqptgwykdlrhyyyrarwelydr
srdphetqnlatdprfaqllemlrdqlakwqwethdpwvcapdgvleeklspqcqplhne
lrs

  • Chain 'F':
    Sequence, based on SEQRES records:
    >4mivF (F:)
mscpvpaccalllvlglcrarprnalllladdggfesgaynnsaiatphldalarrsllf
rnaftsvsssspsraslltglpqhqngmyglhqdvhhfnsfdkvrslplllsqagvrtgi
igkkhvgpetvypfdfayteengsvlqvgrnitrikllvrkflqtqddrpfflyvafhdp
hrcghsqpqygtfcekfgngesgmgripdwtpqaydpldvlvpyfvpntpaaradlaaqy
ttvgrmdqgvglvlqelrdagvlndtlviftsdngipfpsgrtnlywpgtaepllvsspe
hpkrwgqvseayvslldltptildwfsipypsyaifgsktihltgrsllpaleaeplwat
vfgsqshhevtmsypmrsvqhrhfrlvhnlnfkmpfpidqdfyvsptfqdllnrttagqp
tgwykdlrhyyyrarwelydrsrdphetqnlatdprfaqllemlrdqlakwqwethdpwv
capdgvleeklspqcqplhnelrshhhhhh

    Sequence, based on observed residues (ATOM records):
    >4mivF (F:)
prnalllladdggfesgaynnsaiatphldalarrsllfrnaftsvsssspsraslltgl
pqhqngmyglhqdvhhfnsfdkvrslplllsqagvrtgiigkkhvgpetvypfdfaytee
ngsvlqvgrnitrikllvrkflqtqddrpfflyvafhdphrcgqpqygtfcekfgngesg
mgripdwtpqaydpldvlvpyfvpntpaaradlaaqyttvgrmdqgvglvlqelrdagvl
ndtlviftsdngipfpsgrtnlywpgtaepllvsspehpkrwgqvseayvslldltptil
dwfsipypsyaifgsktihltgrsllpaleaeplwatvfgsqshhevtmsypmrsvqhrh
frlvhnlnfkmpfpidqdfyvsptfqdllnrttagqptgwykdlrhyyyrarwelydrsr
dphetqnlatdprfaqllemlrdqlakwqwethdpwvcapdgvleeklspqcqplhne

  • Chain 'G':
    Sequence, based on SEQRES records:
    >4mivG (G:)
mscpvpaccalllvlglcrarprnalllladdggfesgaynnsaiatphldalarrsllf
rnaftsvsssspsraslltglpqhqngmyglhqdvhhfnsfdkvrslplllsqagvrtgi
igkkhvgpetvypfdfayteengsvlqvgrnitrikllvrkflqtqddrpfflyvafhdp
hrcghsqpqygtfcekfgngesgmgripdwtpqaydpldvlvpyfvpntpaaradlaaqy
ttvgrmdqgvglvlqelrdagvlndtlviftsdngipfpsgrtnlywpgtaepllvsspe
hpkrwgqvseayvslldltptildwfsipypsyaifgsktihltgrsllpaleaeplwat
vfgsqshhevtmsypmrsvqhrhfrlvhnlnfkmpfpidqdfyvsptfqdllnrttagqp
tgwykdlrhyyyrarwelydrsrdphetqnlatdprfaqllemlrdqlakwqwethdpwv
capdgvleeklspqcqplhnelrshhhhhh

    Sequence, based on observed residues (ATOM records):
    >4mivG (G:)
prnalllladdggfesgaynnsaiatphldalarrsllfrnaftsvsssspsraslltgl
pqhqngmyglhqdvhhfnsfdkvrslplllsqagvrtgiigkkhvgpetvypfdfaytee
nsvlqvgrnitrikllvrkflqtqddrpfflyvafhdphrcghsqpqygtfcekfgnges
gmgripdwtpqaydpldvlvpyfvpntpaaradlaaqyttvgrmdqgvglvlqelrdagv
lndtlviftsdngipfpsgrtnlywpgtaepllvsspehpkrwgqvseayvslldltpti
ldwfsipypsyaifgsktihltgrsllpaleaeplwatvfgsqshhevtmsypmrsvqhr
hfrlvhnlnfkmpfpidqdfyvsptfqdllnrttagqptgwykdlrhyyyrarwelydrs
rdphetqnlatdprfaqllemlrdqlakwqwethdpwvcapdgvleeklspqcqplhne

  • Chain 'H':
    Sequence, based on SEQRES records:
    >4mivH (H:)
mscpvpaccalllvlglcrarprnalllladdggfesgaynnsaiatphldalarrsllf
rnaftsvsssspsraslltglpqhqngmyglhqdvhhfnsfdkvrslplllsqagvrtgi
igkkhvgpetvypfdfayteengsvlqvgrnitrikllvrkflqtqddrpfflyvafhdp
hrcghsqpqygtfcekfgngesgmgripdwtpqaydpldvlvpyfvpntpaaradlaaqy
ttvgrmdqgvglvlqelrdagvlndtlviftsdngipfpsgrtnlywpgtaepllvsspe
hpkrwgqvseayvslldltptildwfsipypsyaifgsktihltgrsllpaleaeplwat
vfgsqshhevtmsypmrsvqhrhfrlvhnlnfkmpfpidqdfyvsptfqdllnrttagqp
tgwykdlrhyyyrarwelydrsrdphetqnlatdprfaqllemlrdqlakwqwethdpwv
capdgvleeklspqcqplhnelrshhhhhh

    Sequence, based on observed residues (ATOM records):
    >4mivH (H:)
prnalllladdggfesgaynnsaiatphldalarrsllfrnaftsvsssspsraslltgl
pqhqngmyglhqdvhhfnsfdkvrslplllsqagvrtgiigkkhvgpetvypfdfaytee
ngsvlqvgrnitrikllvrkflqtqddrpfflyvafhdphrcghsqpqygtfcekfgnge
sgmgripdwtpqaydpldvlvpyfvpntpaaradlaaqyttvgrmdqgvglvlqelrdag
vlndtlviftsdngipfpsgrtnlywpgtaepllvsspehpkrwgqvseayvslldltpt
ildwfsipypsyaifgsktihltgrsllpaleaeplwatvfgsqshhevtmsypmrsvqh
rhfrlvhnlnfkmpfpidqdfyvsptfqdllnrttagqptgwykdlrhyyyrarwelydr
srdphetqnlatdprfaqllemlrdqlakwqwethdpwvcapdgvleeklspqcqplhne
lr