PDB entry 4mhh

View 4mhh on RCSB PDB site
Description: crystal structure of fab h5m9 in complex with influenza virus hemagglutinin from a/viet nam/1203/2004 (h5n1)
Deposited on 2013-08-29, released 2013-10-02
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 3.56 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hemagglutinin HA1 chain
    Species: Influenza A virus [TaxId:284218]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6DQ33 (4-End)
      • expression tag (1-3)
  • Chain 'B':
    Compound: Hemagglutinin HA2 chain
    Species: Influenza A virus [TaxId:284218]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6DQ33 (0-173)
      • expression tag (174-176)
  • Chain 'C':
    Compound: Hemagglutinin HA1 chain
    Species: Influenza A virus [TaxId:284218]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6DQ33 (4-End)
      • expression tag (1-3)
  • Chain 'D':
    Compound: Hemagglutinin HA2 chain
    Species: Influenza A virus [TaxId:284218]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6DQ33 (0-173)
      • expression tag (174-176)
  • Chain 'E':
    Compound: Hemagglutinin HA1 chain
    Species: Influenza A virus [TaxId:284218]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6DQ33 (4-End)
      • expression tag (1-3)
  • Chain 'F':
    Compound: Hemagglutinin HA2 chain
    Species: Influenza A virus [TaxId:284218]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6DQ33 (0-173)
      • expression tag (174-176)
  • Chain 'G':
    Compound: H5M9 antibody, heavy chain (IgG1)
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4MHH (0-221)
  • Chain 'H':
    Compound: H5M9 antibody, heavy chain (IgG1)
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4MHH (0-221)
  • Chain 'I':
    Compound: H5M9 antibody, light chain (kappa)
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4MHH (0-End)
  • Chain 'J':
    Compound: H5M9 antibody, heavy chain (IgG1)
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4MHH (0-221)
  • Chain 'K':
    Compound: H5M9 antibody, light chain (kappa)
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4MHH (0-End)
  • Chain 'L':
    Compound: H5M9 antibody, light chain (kappa)
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 4MHH (0-End)
  • Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4mhhA (A:)
adpgdqicigyhannsteqvdtimeknvtvthaqdilekkhngklcdldgvkplilrdcs
vagwllgnpmcdefinvpewsyivekanpvndlcypgdfndyeelkhllsrinhfekiqi
ipksswssheaslgvssacpyqgkssffrnvvwlikknstyptikrsynntnqedllvlw
gihhpndaaeqtklyqnpttyisvgtstlnqrlvpriatrskvngqsgrmeffwtilkpn
dainfesngnfiapeyaykivkkgdstimkseleygncntkcqtpmgainssmpfhnihp
ltigecpkyvksnrlvlatglrnspqrerrrkkr

    Sequence, based on observed residues (ATOM records):
    >4mhhA (A:)
dpgdqicigyhannsteqvdtimeknvtvthaqdilekkhngklcdldgvkplilrdcsv
agwllgnpmcdefinvpewsyivekanpvndlcypgdfndyeelkhllsrinhfekiqii
pksswssheaslgvssacpyqgkssffrnvvwlikknstyptikrsynntnqedllvlwg
ihhpndaaeqtklyqnpttyisvgtstlnqrlvpriatrskvngqsgrmeffwtilkpnd
ainfesngnfiapeyaykivkkgdstimkseleygncntkcqtpmgainssmpfhnihpl
tigecpkyvksnrlvlatglrnsp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4mhhB (B:)
glfgaiagfieggwqgmvdgwygyhhsneqgsgyaadkestqkaidgvtnkvnsiidkmn
tqfeavgrefnnlerrienlnkkmedgfldvwtynaellvlmenertldfhdsnvknlyd
kvrlqlrdnakelgngcfefyhkcdnecmesvrngtydypqyseearlkreeissgrlvp
r

    Sequence, based on observed residues (ATOM records):
    >4mhhB (B:)
glfgaiagfieggwqgmvdgwygyhhsneqgsgyaadkestqkaidgvtnkvnsiidkmn
tqfeavgrefnnlerrienlnkkmedgfldvwtynaellvlmenertldfhdsnvknlyd
kvrlqlrdnakelgngcfefyhkcdnecmesvrngtydypqyseearlkreeissgr

  • Chain 'C':
    Sequence, based on SEQRES records:
    >4mhhC (C:)
adpgdqicigyhannsteqvdtimeknvtvthaqdilekkhngklcdldgvkplilrdcs
vagwllgnpmcdefinvpewsyivekanpvndlcypgdfndyeelkhllsrinhfekiqi
ipksswssheaslgvssacpyqgkssffrnvvwlikknstyptikrsynntnqedllvlw
gihhpndaaeqtklyqnpttyisvgtstlnqrlvpriatrskvngqsgrmeffwtilkpn
dainfesngnfiapeyaykivkkgdstimkseleygncntkcqtpmgainssmpfhnihp
ltigecpkyvksnrlvlatglrnspqrerrrkkr

    Sequence, based on observed residues (ATOM records):
    >4mhhC (C:)
dpgdqicigyhannsteqvdtimeknvtvthaqdilekkhngklcdldgvkplilrdcsv
agwllgnpmcdefinvpewsyivekanpvndlcypgdfndyeelkhllsrinhfekiqii
pksswssheaslgvssacpyqgkssffrnvvwlikknstyptikrsynntnqedllvlwg
ihhpndaaeqtklyqnpttyisvgtstlnqrlvpriatrskvngqsgrmeffwtilkpnd
ainfesngnfiapeyaykivkkgdstimkseleygncntkcqtpmgainssmpfhnihpl
tigecpkyvksnrlvlatglrnsp

  • Chain 'D':
    Sequence, based on SEQRES records:
    >4mhhD (D:)
glfgaiagfieggwqgmvdgwygyhhsneqgsgyaadkestqkaidgvtnkvnsiidkmn
tqfeavgrefnnlerrienlnkkmedgfldvwtynaellvlmenertldfhdsnvknlyd
kvrlqlrdnakelgngcfefyhkcdnecmesvrngtydypqyseearlkreeissgrlvp
r

    Sequence, based on observed residues (ATOM records):
    >4mhhD (D:)
glfgaiagfieggwqgmvdgwygyhhsneqgsgyaadkestqkaidgvtnkvnsiidkmn
tqfeavgrefnnlerrienlnkkmedgfldvwtynaellvlmenertldfhdsnvknlyd
kvrlqlrdnakelgngcfefyhkcdnecmesvrngtydypqyseearlkreeissgr

  • Chain 'E':
    Sequence, based on SEQRES records:
    >4mhhE (E:)
adpgdqicigyhannsteqvdtimeknvtvthaqdilekkhngklcdldgvkplilrdcs
vagwllgnpmcdefinvpewsyivekanpvndlcypgdfndyeelkhllsrinhfekiqi
ipksswssheaslgvssacpyqgkssffrnvvwlikknstyptikrsynntnqedllvlw
gihhpndaaeqtklyqnpttyisvgtstlnqrlvpriatrskvngqsgrmeffwtilkpn
dainfesngnfiapeyaykivkkgdstimkseleygncntkcqtpmgainssmpfhnihp
ltigecpkyvksnrlvlatglrnspqrerrrkkr

    Sequence, based on observed residues (ATOM records):
    >4mhhE (E:)
dpgdqicigyhannsteqvdtimeknvtvthaqdilekkhngklcdldgvkplilrdcsv
agwllgnpmcdefinvpewsyivekanpvndlcypgdfndyeelkhllsrinhfekiqii
pksswssheaslgvssacpyqgkssffrnvvwlikknstyptikrsynntnqedllvlwg
ihhpndaaeqtklyqnpttyisvgtstlnqrlvpriatrskvngqsgrmeffwtilkpnd
ainfesngnfiapeyaykivkkgdstimkseleygncntkcqtpmgainssmpfhnihpl
tigecpkyvksnrlvlatglrnsp

  • Chain 'F':
    Sequence, based on SEQRES records:
    >4mhhF (F:)
glfgaiagfieggwqgmvdgwygyhhsneqgsgyaadkestqkaidgvtnkvnsiidkmn
tqfeavgrefnnlerrienlnkkmedgfldvwtynaellvlmenertldfhdsnvknlyd
kvrlqlrdnakelgngcfefyhkcdnecmesvrngtydypqyseearlkreeissgrlvp
r

    Sequence, based on observed residues (ATOM records):
    >4mhhF (F:)
glfgaiagfieggwqgmvdgwygyhhsneqgsgyaadkestqkaidgvtnkvnsiidkmn
tqfeavgrefnnlerrienlnkkmedgfldvwtynaellvlmenertldfhdsnvknlyd
kvrlqlrdnakelgngcfefyhkcdnecmesvrngtydypqyseearlkreeissgr

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records:
    >4mhhG (G:)
evhlqqsgpelvkpgasvkmscktsgytfteytihwmkqshgkslewiggifpnngdtty
nqkfkvratltvgrssstaymdlrsltsedsavyycvrnygssygyfdvwgagttvtvss
akttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsd
lytlsssvtvpsstwpsetvtcnvahpasstkvdkkivprdc

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records:
    >4mhhH (H:)
evhlqqsgpelvkpgasvkmscktsgytfteytihwmkqshgkslewiggifpnngdtty
nqkfkvratltvgrssstaymdlrsltsedsavyycvrnygssygyfdvwgagttvtvss
akttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsd
lytlsssvtvpsstwpsetvtcnvahpasstkvdkkivprdc

  • Chain 'I':
    Sequence, based on SEQRES records:
    >4mhhI (I:)
divltqspgsltvslgqratiscrasesvdnfgksfmhwyqqkpgqspklliyrasnref
giparfngsgsgtdfaltinpveaddvatyfcqqsnedprtfgggtkleikradaaptvs
ifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysms
stltltkdeyerhnsytceathktstspivksfnrnec

    Sequence, based on observed residues (ATOM records):
    >4mhhI (I:)
divltqspgsltvslgqratiscrasesvdnfgksfmhwyqqkpgqspklliyrasnref
giparfngsgsgtdfaltinpveaddvatyfcqqsnedprtfgggtkleikradaaptvs
ifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysms
stltltkdeyerhnsytceathktstspivksfnrne

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records:
    >4mhhJ (J:)
evhlqqsgpelvkpgasvkmscktsgytfteytihwmkqshgkslewiggifpnngdtty
nqkfkvratltvgrssstaymdlrsltsedsavyycvrnygssygyfdvwgagttvtvss
akttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsd
lytlsssvtvpsstwpsetvtcnvahpasstkvdkkivprdc

  • Chain 'K':
    Sequence, based on SEQRES records:
    >4mhhK (K:)
divltqspgsltvslgqratiscrasesvdnfgksfmhwyqqkpgqspklliyrasnref
giparfngsgsgtdfaltinpveaddvatyfcqqsnedprtfgggtkleikradaaptvs
ifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysms
stltltkdeyerhnsytceathktstspivksfnrnec

    Sequence, based on observed residues (ATOM records):
    >4mhhK (K:)
divltqspgsltvslgqratiscrasesvdnfgksfmhwyqqkpgqspklliyrasnref
giparfngsgsgtdfaltinpveaddvatyfcqqsnedprtfgggtkleikradaaptvs
ifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysms
stltltkdeyerhnsytceathktstspivksfnrne

  • Chain 'L':
    Sequence, based on SEQRES records:
    >4mhhL (L:)
divltqspgsltvslgqratiscrasesvdnfgksfmhwyqqkpgqspklliyrasnref
giparfngsgsgtdfaltinpveaddvatyfcqqsnedprtfgggtkleikradaaptvs
ifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysms
stltltkdeyerhnsytceathktstspivksfnrnec

    Sequence, based on observed residues (ATOM records):
    >4mhhL (L:)
divltqspgsltvslgqratiscrasesvdnfgksfmhwyqqkpgqspklliyrasnref
giparfngsgsgtdfaltinpveaddvatyfcqqsnedprtfgggtkleikradaaptvs
ifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysms
stltltkdeyerhnsytceathktstspivksfnrne