PDB entry 4mg5

View 4mg5 on RCSB PDB site
Description: Crystal structure of hERa-LBD (Y537S) in complex with chlordecone
Deposited on 2013-08-28, released 2014-09-03
The last revision was dated 2014-12-17, with a file datestamp of 2014-12-12.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.199
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR, ESR1, NR3A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03372
      • engineered mutation (239)
  • Chain 'B':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR, ESR1, NR3A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03372
      • engineered mutation (239)
  • Chain 'C':
    Compound: Nuclear receptor coactivator 1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Nuclear receptor coactivator 1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: EDO, 27E, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4mg5A (A:)
gshmkknslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhm
inwakrvpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkc
vegmveifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihr
vldkitdtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvpls
dlllemldahrlhap

    Sequence, based on observed residues (ATOM records):
    >4mg5A (A:)
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytfstlksleekdhihrvldkitdtl
ihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdlllemlda
h

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4mg5B (B:)
gshmkknslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhm
inwakrvpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkc
vegmveifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihr
vldkitdtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvpls
dlllemldahrlhap

    Sequence, based on observed residues (ATOM records):
    >4mg5B (B:)
knslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwak
rvpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmv
eifdmllatssrfrmmnlqgeefvclksiillnsgvytfkdhihrvldkitdtlihlmak
agltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplsdlllemldahr

  • Chain 'C':
    Sequence, based on SEQRES records:
    >4mg5C (C:)
rhkilhrllqegs

    Sequence, based on observed residues (ATOM records):
    >4mg5C (C:)
kilhrllqe

  • Chain 'D':
    Sequence, based on SEQRES records:
    >4mg5D (D:)
rhkilhrllqegs

    Sequence, based on observed residues (ATOM records):
    >4mg5D (D:)
hkilhrllqe