PDB entry 4mf3

View 4mf3 on RCSB PDB site
Description: Crystal Structure of Human GRIK1 complexed with a 6-(tetrazolyl)aryl decahydroisoquinoline antagonist
Class: signaling protein
Keywords: Protein-Ligand Complex, Ligand Gated Ion Channel, Glutamate Receptor, Glutamate binding, none, Membrane, SIGNALING PROTEIN
Deposited on 2013-08-27, released 2014-05-07
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-05-07, with a file datestamp of 2014-05-02.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.238
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor ionotropic, kainate 1
    Species: Homo sapiens [TaxId:9606]
    Gene: Grik1, Glur5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4mf3a_
  • Chain 'B':
    Compound: Glutamate receptor ionotropic, kainate 1
    Species: Homo sapiens [TaxId:9606]
    Gene: Grik1, Glur5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4mf3b_
  • Heterogens: SXI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4mf3A (A:)
slanrtlivttileepyvmyrksdkplygndrfegycldllkelsnilgfiydvklvpdg
kygaqndkgewngmvkelidhradlavapltityvrekvidfskpfmtlgisilyrkgtp
idsaddlakqtkieygavrdgstmtffkkskistyekmwafmssrqqtalvrnsdegiqr
vlttdyallmestsieyvtqrncnltqigglidskgygvgtpigspyrdkitiailqlqe
egklhmmkekwwrgngcpeeg

    Sequence, based on observed residues (ATOM records): (download) 
    >4mf3A (A:)
slanrtlivttileepyvmyrksdkplygndrfegycldllkelsnilgfiydvklvpdg
kygaqndkgewngmvkelidhradlavapltityvrekvidfskpfmtlgisilyrkgtp
idsaddlakqtkieygavrdgstmtffkkskistyekmwafmssrqqtalvrnsdegiqr
vlttdyallmestsieyvtqrncnltqigglidskgygvgtpigspyrdkitiailqlqe
egklhmmkekwwrgngcp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4mf3B (B:)
slanrtlivttileepyvmyrksdkplygndrfegycldllkelsnilgfiydvklvpdg
kygaqndkgewngmvkelidhradlavapltityvrekvidfskpfmtlgisilyrkgtp
idsaddlakqtkieygavrdgstmtffkkskistyekmwafmssrqqtalvrnsdegiqr
vlttdyallmestsieyvtqrncnltqigglidskgygvgtpigspyrdkitiailqlqe
egklhmmkekwwrgngcpeeg

    Sequence, based on observed residues (ATOM records): (download) 
    >4mf3B (B:)
slanrtlivttileepyvmyrksdkplygndrfegycldllkelsnilgfiydvklvpdg
kygaqndkgewngmvkelidhradlavapltityvrekvidfskpfmtlgisilyrkgtp
idsaddlakqtkieygavrdgstmtffkkskistyekmwafmssrqqtalvrnsdegiqr
vlttdyallmestsieyvtqrncnltqigglidskgygvgtpigspyrdkitiailqlqe
egklhmmkekwwrgngcp