PDB entry 4mcc

View 4mcc on RCSB PDB site
Description: HinTrmD in complex with N-[4-(AMINOMETHYL)BENZYL]-4-OXO-3,4-DIHYDROTHIENO[2,3-D]PYRIMIDINE-5-CARBOXAMIDE
Class: transferase/transferase inhibitor
Keywords: trefoil, TrmD, SAM, SAH, Sinefungin, HMT, Structural Genomics, N/A, transferase-transferase inhibitor complex
Deposited on 2013-08-21, released 2013-09-04
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-10-09, with a file datestamp of 2013-10-04.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.182
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tRNA (guanine-N(1)-)-methyltransferase
    Species: Haemophilus influenzae [TaxId:71421]
    Gene: HI_0202, trmD
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4mcca_
  • Chain 'B':
    Compound: tRNA (guanine-N(1)-)-methyltransferase
    Species: Haemophilus influenzae [TaxId:71421]
    Gene: HI_0202, trmD
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4mccb_
  • Heterogens: 21X, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4mccA (A:)
mwigvislfpemfkaitefgvtgravkhnllkvecwnprdftfdkhktvddrpygggpgm
lmmvqplrdaihtakaaagegakviylspqgrkldqggvtelaqnqklilvcgryegide
rliqteideewsigdyvltggelpamtlidavarfipgvlgkqasaeedsfadglldcph
ytrpevlegltvppvlmsghheeirkwrlkqslqrtwlrrpelleglaltdeqrkllkea
qaehns

    Sequence, based on observed residues (ATOM records): (download) 
    >4mccA (A:)
mwigvislfpemfkaitefgvtgravkhnllkvecwnprdftfdkhktvddrpygggpgm
lmmvqplrdaihtakaaagegakviylspqgrkldqggvtelaqnqklilvcgryegide
rliqteideewsigdyvltggelpamtlidavarfipgvlglldcphytrpevlegltvp
pvlmsghheeirkwrlkqslqrtwlr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4mccB (B:)
mwigvislfpemfkaitefgvtgravkhnllkvecwnprdftfdkhktvddrpygggpgm
lmmvqplrdaihtakaaagegakviylspqgrkldqggvtelaqnqklilvcgryegide
rliqteideewsigdyvltggelpamtlidavarfipgvlgkqasaeedsfadglldcph
ytrpevlegltvppvlmsghheeirkwrlkqslqrtwlrrpelleglaltdeqrkllkea
qaehns

    Sequence, based on observed residues (ATOM records): (download) 
    >4mccB (B:)
mwigvislfpemfkaitefgvtgravkhnllkvecwnprdftfdkhktvddrpygggpgm
lmmvqplrdaihtakaaagegakviylspqgrkldqggvtelaqnqklilvcgryegide
rliqteideewsigdyvltggelpamtlidavarfipgvldglldcphytrpevlegltv
ppvlmsghheeirkwrlkqslqrtwlrrpelleglaltdeqrkllkeaqaehn