PDB entry 4mb8

View 4mb8 on RCSB PDB site
Description: Evolutionary history and metabolic insights of ancient mammalian uricases
Class: oxidoreductase
Keywords: Uric acid oxidase, lysozome, oxidoreductase
Deposited on 2013-08-19, released 2014-02-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-22, with a file datestamp of 2019-05-17.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Uricase
    Species: unclassified Mammalia [TaxId:1002697]
    Gene: Phylogenetically predicted sequence for the mammalian uricase ancestor, UOX
    Database cross-references and differences (RAF-indexed):
    • PDB 4MB8
    Domains in SCOPe 2.08: d4mb8a1, d4mb8a2
  • Chain 'B':
    Compound: Uricase
    Species: unclassified Mammalia [TaxId:1002697]
    Gene: Phylogenetically predicted sequence for the mammalian uricase ancestor, UOX
    Database cross-references and differences (RAF-indexed):
    • PDB 4MB8
    Domains in SCOPe 2.08: d4mb8b1, d4mb8b2
  • Chain 'C':
    Compound: Uricase
    Species: unclassified Mammalia [TaxId:1002697]
    Gene: Phylogenetically predicted sequence for the mammalian uricase ancestor, UOX
    Database cross-references and differences (RAF-indexed):
    • PDB 4MB8
    Domains in SCOPe 2.08: d4mb8c1, d4mb8c2
  • Chain 'D':
    Compound: Uricase
    Species: unclassified Mammalia [TaxId:1002697]
    Gene: Phylogenetically predicted sequence for the mammalian uricase ancestor, UOX
    Database cross-references and differences (RAF-indexed):
    • PDB 4MB8
    Domains in SCOPe 2.08: d4mb8d1, d4mb8d2
  • Heterogens: ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4mb8A (A:)
mahyhndykkndevefvrtgygkdmvkvlhiqrdgkyhsikevatsvqltlsskkdylhg
dnsdiiptdtikntvhvlakfkgiksieafamnicehflssfnhviraqvyveevpwkrf
ekngvkhvhafihtptgthfceveqmksgppvihsgikdlkvlkttqsgfegfikdqftt
lpevkdrcfatqvyckwryhqgrdvdfeatwdtvrdivlkkfagpydkgeyspsvqktly
diqvlslsrvpeiedmeislpnihyfnidmskmglinkeevllpldnpygkitgtvkrkl
ssrl

    Sequence, based on observed residues (ATOM records): (download) 
    >4mb8A (A:)
vefvrtgygkdmvkvlhiqrdgkyhsikevatsvqltlsskkdylhgdnsdiiptdtikn
tvhvlakfkgiksieafamnicehflssfnhviraqvyveevpwkrfekngvkhvhafih
tptgthfceveqmksgppvihsgikdlkvlkttqsgfegfikdqfttlpevkdrcfatqv
yckwryhqgrdvdfeatwdtvrdivlkkfagpydkgeyspsvqktlydiqvlslsrvpei
edmeislpnihyfnidmskmglinkeevllpldnpygkitgtvkr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4mb8B (B:)
mahyhndykkndevefvrtgygkdmvkvlhiqrdgkyhsikevatsvqltlsskkdylhg
dnsdiiptdtikntvhvlakfkgiksieafamnicehflssfnhviraqvyveevpwkrf
ekngvkhvhafihtptgthfceveqmksgppvihsgikdlkvlkttqsgfegfikdqftt
lpevkdrcfatqvyckwryhqgrdvdfeatwdtvrdivlkkfagpydkgeyspsvqktly
diqvlslsrvpeiedmeislpnihyfnidmskmglinkeevllpldnpygkitgtvkrkl
ssrl

    Sequence, based on observed residues (ATOM records): (download) 
    >4mb8B (B:)
vefvrtgygkdmvkvlhiqrdgkyhsikevatsvqltlsskkdylhgdnsdiiptdtikn
tvhvlakfkgiksieafamnicehflssfnhviraqvyveevpwkrfekngvkhvhafih
tptgthfceveqmksgppvihsgikdlkvlkttqsgfegfikdqfttlpevkdrcfatqv
yckwryhqgrdvdfeatwdtvrdivlkkfagpydkgeyspsvqktlydiqvlslsrvpei
edmeislpnihyfnidmskmglinkeevllpldnpygkitgtvkrk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4mb8C (C:)
mahyhndykkndevefvrtgygkdmvkvlhiqrdgkyhsikevatsvqltlsskkdylhg
dnsdiiptdtikntvhvlakfkgiksieafamnicehflssfnhviraqvyveevpwkrf
ekngvkhvhafihtptgthfceveqmksgppvihsgikdlkvlkttqsgfegfikdqftt
lpevkdrcfatqvyckwryhqgrdvdfeatwdtvrdivlkkfagpydkgeyspsvqktly
diqvlslsrvpeiedmeislpnihyfnidmskmglinkeevllpldnpygkitgtvkrkl
ssrl

    Sequence, based on observed residues (ATOM records): (download) 
    >4mb8C (C:)
vefvrtgygkdmvkvlhiqrdgkyhsikevatsvqltlsskkdylhgdnsdiiptdtikn
tvhvlakfkgiksieafamnicehflssfnhviraqvyveevpwkrfekngvkhvhafih
tptgthfceveqmksgppvihsgikdlkvlkttqsgfegfikdqfttlpevkdrcfatqv
yckwryhqgvdfeatwdtvrdivlkkfagpydkgeyspsvqktlydiqvlslsrvpeied
meislpnihyfnidmskmglinkeevllpldnpygkitgtvkrkl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4mb8D (D:)
mahyhndykkndevefvrtgygkdmvkvlhiqrdgkyhsikevatsvqltlsskkdylhg
dnsdiiptdtikntvhvlakfkgiksieafamnicehflssfnhviraqvyveevpwkrf
ekngvkhvhafihtptgthfceveqmksgppvihsgikdlkvlkttqsgfegfikdqftt
lpevkdrcfatqvyckwryhqgrdvdfeatwdtvrdivlkkfagpydkgeyspsvqktly
diqvlslsrvpeiedmeislpnihyfnidmskmglinkeevllpldnpygkitgtvkrkl
ssrl

    Sequence, based on observed residues (ATOM records): (download) 
    >4mb8D (D:)
vefvrtgygkdmvkvlhiqrdgkyhsikevatsvqltlsskkdylhgdnsdiiptdtikn
tvhvlakfkgiksieafamnicehflssfnhviraqvyveevpwkrfekngvkhvhafih
tptgthfceveqmksgppvihsgikdlkvlkttqsgfegfikdqfttlpevkdrcfatqv
yckwryhqgrdvdfeatwdtvrdivlkkfagpydkgeyspsvqktlydiqvlslsrvpei
edmeislpnihyfnidmskmglinkeevllpldnpygkitgtvkrklssr