PDB entry 4m69

View 4m69 on RCSB PDB site
Description: Crystal structure of the mouse RIP3-MLKL complex
Class: transferase/signaling protein
Keywords: kinase, phosphorylation, TRANSFERASE-SIGNALING PROTEIN complex
Deposited on 2013-08-09, released 2013-10-16
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-11-06, with a file datestamp of 2013-11-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.222
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Receptor-interacting serine/threonine-protein kinase 3
    Species: Mus musculus [TaxId:10090]
    Gene: Ripk3
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: mixed lineage kinase domain-like protein
    Species: Mus musculus [TaxId:10090]
    Gene: Mlkl
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4m69b_
  • Heterogens: ANP, SO4, MG, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4m69B (B:)
    qikeipkehlgppwtklktskmstiyrgeyhrspvtikvfnnpqaesvgivrftfndeik
    tmkkfdspnilrifgicidqtvkppefsivmeycelgtlrelldrekdltmsvrsllvlr
    aarglyrlhhsetlhrnissssflvaggyqvklagfelsktqnsisrtakstkaerssst
    iyvsperlknpfclydikaeiysfgivlweiatgkipfegcdskkirelvaedkkqepvg
    qdcpellreiinecrahepsqrpsvdgilerlsaveestdkkv
    

    Sequence, based on observed residues (ATOM records): (download)
    >4m69B (B:)
    qikeipkehlgppwtklktskmstiyrgeyhrspvtikvfnnpqaesvgivrftfndeik
    tmkkfdspnilrifgicidqtvkppefsivmeycelgtlrelldrekdltmsvrsllvlr
    aarglyrlhhsetlhrnissssflvaggyqvklagfelsktqnssstiyvsperlknpfc
    lydikaeiysfgivlweiatgkipfegcdskkirelvaedkkqepvgqdcpellreiine
    crahepsqrpsvdgilerlsavee