PDB entry 4m5z

View 4m5z on RCSB PDB site
Description: Crystal structure of broadly neutralizing antibody 5J8 bound to 2009 pandemic influenza hemagglutinin, HA1 subunit
Class: viral protein/immune system
Keywords: hemagglutinin, immunoglobulin fold, VIRAL PROTEIN-IMMUNE SYSTEM complex
Deposited on 2013-08-08, released 2013-09-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-11-06, with a file datestamp of 2013-11-01.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.193
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hemagglutinin HA1 chain
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Fab 5J8 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4M5Z (0-End)
    Domains in SCOPe 2.08: d4m5zh_
  • Chain 'L':
    Compound: Fab 5J8 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4M5Z (0-End)
    Domains in SCOPe 2.08: d4m5zl1, d4m5zl2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4m5zH (H:)
evqlvesgpglvkpsdilsltcavsgysissnyywgwirqppgkglewigsiyhsgstyy
kpslesrlgisvdtsknqfslklsfvsaadtavyycarhvrsgypdtayyfdkwgqgtlv
tvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpav
lqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkschhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4m5zH (H:)
evqlvesgpglvkpsdilsltcavsgysissnyywgwirqppgkglewigsiyhsgstyy
kpslesrlgisvdtsknqfslklsfvsaadtavyycarhvrsgypdtayyfdkwgqgtlv
tvssastkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepks

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >4m5zL (L:)
syvltqppsvsvapgetariscggnnigtkvlhwyqqtpgqapvlvvyddsdrpsgiper
fsgsnsgntatltisrvevgdeadyycqvwdistdqavfgggtkltvlgqpkaapsvtlf
ppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassyl
sltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >4m5zL (L:)
syvltqppsvsvapgetariscggnnigtkvlhwyqqtpgqapvlvvyddsdrpsgiper
fsgsnsgntatltisrvevgdeadyycqvwdistdqavfgggtkltvlgqpkaapsvtlf
ppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassyl
sltpeqwkshrsyscqvthegstvektvapte