PDB entry 4m5t

View 4m5t on RCSB PDB site
Description: disulfide trapped human alphab crystallin core domain in complex with c-terminal peptide
Deposited on 2013-08-08, released 2014-04-09
The last revision was dated 2019-07-17, with a file datestamp of 2019-07-12.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alpha-crystallin b chain
    Species: Homo sapiens [TaxId:9606]
    Gene: CRYA2, CRYAB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02511 (1-End)
      • expression tag (0)
      • engineered mutation (50)
  • Chain 'B':
    Compound: alpha-crystallin b chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: alpha-crystallin b chain
    Species: Homo sapiens [TaxId:9606]
    Gene: CRYA2, CRYAB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02511 (1-End)
      • expression tag (0)
      • engineered mutation (50)
  • Chain 'D':
    Compound: alpha-crystallin b chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: alpha-crystallin b chain
    Species: Homo sapiens [TaxId:9606]
    Gene: CRYA2, CRYAB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02511 (1-End)
      • expression tag (0)
      • engineered mutation (50)
  • Chain 'F':
    Compound: alpha-crystallin b chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: alpha-crystallin b chain
    Species: Homo sapiens [TaxId:9606]
    Gene: CRYA2, CRYAB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02511 (1-End)
      • expression tag (0)
      • engineered mutation (50)
  • Chain 'H':
    Compound: alpha-crystallin b chain
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4m5tA (A:)
gmrlekdrfsvnldvkhfspeelkvkvlgdvievhgkheerqdehgfisrcfhrkyripa
dvdpltitsslssdgvltvngprkqvs

    Sequence, based on observed residues (ATOM records):
    >4m5tA (A:)
gmrlekdrfsvnldvkhfspeelkvkvlgdvievhgkheergfisrcfhrkyripadvdp
ltitsslssdgvltvngprkqv

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >4m5tB (B:)
ertipitre

  • Chain 'C':
    Sequence, based on SEQRES records:
    >4m5tC (C:)
gmrlekdrfsvnldvkhfspeelkvkvlgdvievhgkheerqdehgfisrcfhrkyripa
dvdpltitsslssdgvltvngprkqvs

    Sequence, based on observed residues (ATOM records):
    >4m5tC (C:)
gmrlekdrfsvnldvkhfspeelkvkvlgdvievhgkheerqehgfisrcfhrkyripad
vdpltitsslssdgvltvngprkqv

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >4m5tD (D:)
ertipitre

  • Chain 'E':
    Sequence, based on SEQRES records:
    >4m5tE (E:)
gmrlekdrfsvnldvkhfspeelkvkvlgdvievhgkheerqdehgfisrcfhrkyripa
dvdpltitsslssdgvltvngprkqvs

    Sequence, based on observed residues (ATOM records):
    >4m5tE (E:)
gmrlekdrfsvnldvkhfspeelkvkvlgdvievhgkheerqdehgfisrcfhrkyripa
dvdpltitsslssdgvltvngprkq

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records:
    >4m5tF (F:)
ertipitre

  • Chain 'G':
    Sequence, based on SEQRES records:
    >4m5tG (G:)
gmrlekdrfsvnldvkhfspeelkvkvlgdvievhgkheerqdehgfisrcfhrkyripa
dvdpltitsslssdgvltvngprkqvs

    Sequence, based on observed residues (ATOM records):
    >4m5tG (G:)
gmrlekdrfsvnldvkhfspeelkvkvlgdvievhgkheerqdehgfisrcfhrkyripa
dvdpltitsslssdgvltvngprkqv

  • Chain 'H':
    Sequence, based on SEQRES records:
    >4m5tH (H:)
ertipitre

    Sequence, based on observed residues (ATOM records):
    >4m5tH (H:)
ertipitr