PDB entry 4m5j

View 4m5j on RCSB PDB site
Description: The Identification, Analysis and Structure-Based Development of Novel Inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase
Class: transferase/transferase inhibitor
Keywords: FOLATE BIOSYNTHESIS, Diphosphotransferases, PTERIN, ATP binding, Inhibitor, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2013-08-08, released 2014-04-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-12-14, with a file datestamp of 2016-12-09.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
    Species: Escherichia coli [TaxId:83333]
    Gene: folK, b0142, JW0138
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4m5ja_
  • Heterogens: APC, YH5, MG, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4m5jA (A:)

    Sequence, based on observed residues (ATOM records): (download)
    >4m5jA (A:)