PDB entry 4m3q

View 4m3q on RCSB PDB site
Description: crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase mer in complex with inhibitor unc1917
Deposited on 2013-08-06, released 2013-11-27
The last revision was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 2.72 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase Mer
    Species: Homo sapiens [TaxId:9606]
    Gene: MER, MERTK
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Tyrosine-protein kinase Mer
    Species: Homo sapiens [TaxId:9606]
    Gene: MER, MERTK
    Database cross-references and differences (RAF-indexed):
  • Heterogens: CL, MG, 24K, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4m3qA (A:)
mgsshhhhhhssglvprgseelqnkledvvidrnllilgkilgegefgsvmegnlkqedg
tslkvavktmkldnssqreieeflseaacmkdfshpnvirllgvciemssqgipkpmvil
pfmkygdlhtyllysrletgpkhiplqtllkfmvdialgmeylsnrnflhrdlaarncml
rddmtvcvadfglskkiysgdyyrqgriakmpvkwiaiesladrvytsksdvwafgvtmw
eiatrgmtpypgvqnhemydyllhghrlkqpedcldelyeimyscwrtdpldrptfsvlr
lqleklleslpdv

    Sequence, based on observed residues (ATOM records):
    >4m3qA (A:)
edvvidrnllilgkilgegefgsvmegnlkqedgtslkvavktcmkdfshpnvirllgvc
iemssqgipkpmvilpfmkygdlhtyllysrletgpkhiplqtllkfmvdialgmeylsn
rnflhrdlaarncmlrddmtvcvadfpvkwiaieslrvytsksdvwafgvtmweiatrgm
tpypgvqnhemydyllhghrlkqpedcldelyeimyscwrtdpldrptfsvlrlqlekll
esl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4m3qB (B:)
mgsshhhhhhssglvprgseelqnkledvvidrnllilgkilgegefgsvmegnlkqedg
tslkvavktmkldnssqreieeflseaacmkdfshpnvirllgvciemssqgipkpmvil
pfmkygdlhtyllysrletgpkhiplqtllkfmvdialgmeylsnrnflhrdlaarncml
rddmtvcvadfglskkiysgdyyrqgriakmpvkwiaiesladrvytsksdvwafgvtmw
eiatrgmtpypgvqnhemydyllhghrlkqpedcldelyeimyscwrtdpldrptfsvlr
lqleklleslpdv

    Sequence, based on observed residues (ATOM records):
    >4m3qB (B:)
ledvvidrnllilgkilgsvmegnlkslkvavktmflseaacmkdfshpnvirllgvcik
pmvilpfmkygdlhtyllysrletgpkhiplqtllkfmvdialgmeylsnrnflhrdlaa
rncmlrddmtvcvadfgpvkwiaiesladrvytsksdvwafgvtmweiatrgmtpypgvq
nhemydyllhghrlkqpedcldelyeimyscwrtdpldrptfsvlrlqlekllesl