PDB entry 4m2b

View 4m2b on RCSB PDB site
Description: Crystal structure of L281D mutant of udp-glucose pyrophosphorylase from leishmania major in complex with udp-glc
Deposited on 2013-08-05, released 2014-01-29
The last revision was dated 2014-02-19, with a file datestamp of 2014-02-14.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.178
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: UDP-glucose pyrophosphorylase
    Species: Leishmania major [TaxId:5664]
    Gene: LMJF_18_0990, UGP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q4QDU3
      • engineered mutation (280)
  • Heterogens: UPG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4m2bA (A:)
mendmkslsaaaqacvkkmrdakvneacirtfiaqhvmvskgetgsipdsaimpvdslda
ldsltiecdnavlqstvvlklngglgtgmglcdaktllevkdgktfldftalqvqylrqh
csehlrfmlmdsfntsastksflkarypwlyqvfdsevelmqnqvpkilqdtlepaawae
npayewappghgdiytalygsgklqelveqgyrymfvsngdnlgatidkrvlaymekeki
dflmevcrrtesdkkgghlarqtvyvkgkdgqpdaekrvldlresaqcpkadmesfqdin
kysffntnnlwirlpvlletmqehggtlplpvirnektvdssnsaspkvyqletamgaai
amfesasaivvprsrfapvktcadllalrsdayvvtddfrlvlddrchghppvvdldsah
ykmmngfeklvqhgvpslveckrvtvkglvqfgagnvltgtvtientdsasafvipdgak
lndttaspqqstnkmrplehhhhhh

    Sequence, based on observed residues (ATOM records):
    >4m2bA (A:)
kslsaaaqacvkkmrdakvneacirtfiaqhvmvskgetgsipdsaimpvdsldaldslt
iecdnavlqstvvlklngglgtgmglcdaktllevkdgktfldftalqvqylrqhcsehl
rfmlmdsfntsastksflkarypwlyqvfdsevelmqnqvpkilqdtlepaawaenpaye
wappghgdiytalygsgklqelveqgyrymfvsngdnlgatidkrvlaymekekidflme
vcrrtesdkkgghlarqtvyvkgkdgqpdaekrvldlresaqcpkadmesfqdinkysff
ntnnlwirlpvlletmqehggtlplpvirnektvdssnsaspkvyqletamgaaiamfes
asaivvprsrfapvktcadllalrsdayvvtddfrlvlddrchghppvvdldsahykmmn
gfeklvqhgvpslveckrvtvkglvqfgagnvltgtvtientdsasafvipdgaklndtt
asp