PDB entry 4m1m

View 4m1m on RCSB PDB site
Description: Corrected Structure of Mouse P-glycoprotein
Deposited on 2013-08-03, released 2013-11-13
The last revision was dated 2014-01-01, with a file datestamp of 2013-12-27.
Experiment type: XRAY
Resolution: 3.8 Å
R-factor: 0.217
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Multidrug resistance protein 1a
    Species: Mus musculus [TaxId:10090]
    Gene: Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21447
      • conflict (82)
      • conflict (86)
      • conflict (89)
      • conflict (951)
  • Chain 'B':
    Compound: Multidrug resistance protein 1a
    Species: Mus musculus [TaxId:10090]
    Gene: Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21447
      • conflict (82)
      • conflict (86)
      • conflict (89)
      • conflict (951)
  • Heterogens: HG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4m1mA (A:)
meleedlkgradknfskmgkkskkekkekkpavsvltmfryagwldrlymlvgtlaaiih
gvalplmmlifgdmtdsfasvgqvskqstqmseadkramfakleeemttyayyytgigag
vlivayiqvsfwclaagrqihkirqkffhaimnqeigwfdvhdvgelntrltddvskine
gigdkigmffqamatffggfiigftrgwkltlvilaispvlglsagiwakilssftdkel
hayakagavaeevlaairtviafggqkkelerynnnleeakrlgikkaitanismgaafl
liyasyalafwygtslviskeysigqvltvffsvligafsvgqaspnieafanargaaye
vfkiidnkpsidsfsksghkpdniqgnlefknihfsypsrkevqilkglnlkvksgqtva
lvgnsgcgksttvqlmqrlydpldgmvsidgqdirtinvrylreiigvvsqepvlfatti
aenirygredvtmdeiekavkeanaydfimklphqfdtlvgergaqlsggqkqriaiara
lvrnpkillldeatsaldteseavvqaaldkaregrttiviahrlstvrnadviagfdgg
viveqgnhdelmrekgiyfklvmtqtagneielgneackskdeidnldmsskdsgsslir
rrstrksicgphdqdrklstkealdedvppasfwrilklnstewpyfvvgifcaiinggl
qpafsvifskvvgvftnggppetqrqnsnlfsllflilgiisfitfflqgftfgkageil
tkrlrymvfksmlrqdvswfddpknttgalttrlandaaqvkgatgsrlavifqnianlg
tgiiisliygwqltllllaivpiiaiagvvemkmlsgqalkdkkelegsgkiateaienf
rtvvsltreqkfetmyaqslqipyrnamkkahvfgitfsftqammyfsyaaafrfgaylv
tqqlmtfenvllvfsaivfgamavgqvssfapdyakatvsashiiriiektpeidsystq
glkpnmlegnvqfsgvvfnyptrpsipvlqglslevkkgqtlalvgssgcgkstvvqlle
rfydpmagsvfldgkeikqlnvqwlraqlgivsqepilfdcsiaeniaygdnsrvvsyee
ivraakeanihqfidslpdkyntrvgdkgtqlsggqkqriaiaralvrqphillldeats
aldtesekvvqealdkaregrtciviahrlstiqnadlivviqngkvkehgthqqllaqk
giyfsmvsvqagakrshhhhhh

    Sequence, based on observed residues (ATOM records):
    >4m1mA (A:)
kpavsvltmfryagwldrlymlvgtlaaiihgvalplmmlifgdmtdsfasvgqvskqst
qmseadkramfakleeemttyayyytgigagvlivayiqvsfwclaagrqihkirqkffh
aimnqeigwfdvhdvgelntrltddvskinegigdkigmffqamatffggfiigftrgwk
ltlvilaispvlglsagiwakilssftdkelhayakagavaeevlaairtviafggqkke
lerynnnleeakrlgikkaitanismgaaflliyasyalafwygtslviskeysigqvlt
vffsvligafsvgqaspnieafanargaayevfkiidnkpsidsfsksghkpdniqgnle
fknihfsypsrkevqilkglnlkvksgqtvalvgnsgcgksttvqlmqrlydpldgmvsi
dgqdirtinvrylreiigvvsqepvlfattiaenirygredvtmdeiekavkeanaydfi
mklphqfdtlvgergaqlsggqkqriaiaralvrnpkillldeatsaldteseavvqaal
dkaregrttiviahrlstvrnadviagfdggviveqgnhdelmrekgiyfklvmtqtkea
ldedvppasfwrilklnstewpyfvvgifcaiingglqpafsvifskvvgvftnggppet
qrqnsnlfsllflilgiisfitfflqgftfgkageiltkrlrymvfksmlrqdvswfddp
knttgalttrlandaaqvkgatgsrlavifqnianlgtgiiisliygwqltllllaivpi
iaiagvvemkmlsgqalkdkkelegsgkiateaienfrtvvsltreqkfetmyaqslqip
yrnamkkahvfgitfsftqammyfsyaaafrfgaylvtqqlmtfenvllvfsaivfgama
vgqvssfapdyakatvsashiiriiektpeidsystqglkpnmlegnvqfsgvvfnyptr
psipvlqglslevkkgqtlalvgssgcgkstvvqllerfydpmagsvfldgkeikqlnvq
wlraqlgivsqepilfdcsiaeniaygdnsrvvsyeeivraakeanihqfidslpdkynt
rvgdkgtqlsggqkqriaiaralvrqphillldeatsaldtesekvvqealdkaregrtc
iviahrlstiqnadlivviqngkvkehgthqqllaqkgiyfsmvsvqa

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4m1mB (B:)
meleedlkgradknfskmgkkskkekkekkpavsvltmfryagwldrlymlvgtlaaiih
gvalplmmlifgdmtdsfasvgqvskqstqmseadkramfakleeemttyayyytgigag
vlivayiqvsfwclaagrqihkirqkffhaimnqeigwfdvhdvgelntrltddvskine
gigdkigmffqamatffggfiigftrgwkltlvilaispvlglsagiwakilssftdkel
hayakagavaeevlaairtviafggqkkelerynnnleeakrlgikkaitanismgaafl
liyasyalafwygtslviskeysigqvltvffsvligafsvgqaspnieafanargaaye
vfkiidnkpsidsfsksghkpdniqgnlefknihfsypsrkevqilkglnlkvksgqtva
lvgnsgcgksttvqlmqrlydpldgmvsidgqdirtinvrylreiigvvsqepvlfatti
aenirygredvtmdeiekavkeanaydfimklphqfdtlvgergaqlsggqkqriaiara
lvrnpkillldeatsaldteseavvqaaldkaregrttiviahrlstvrnadviagfdgg
viveqgnhdelmrekgiyfklvmtqtagneielgneackskdeidnldmsskdsgsslir
rrstrksicgphdqdrklstkealdedvppasfwrilklnstewpyfvvgifcaiinggl
qpafsvifskvvgvftnggppetqrqnsnlfsllflilgiisfitfflqgftfgkageil
tkrlrymvfksmlrqdvswfddpknttgalttrlandaaqvkgatgsrlavifqnianlg
tgiiisliygwqltllllaivpiiaiagvvemkmlsgqalkdkkelegsgkiateaienf
rtvvsltreqkfetmyaqslqipyrnamkkahvfgitfsftqammyfsyaaafrfgaylv
tqqlmtfenvllvfsaivfgamavgqvssfapdyakatvsashiiriiektpeidsystq
glkpnmlegnvqfsgvvfnyptrpsipvlqglslevkkgqtlalvgssgcgkstvvqlle
rfydpmagsvfldgkeikqlnvqwlraqlgivsqepilfdcsiaeniaygdnsrvvsyee
ivraakeanihqfidslpdkyntrvgdkgtqlsggqkqriaiaralvrqphillldeats
aldtesekvvqealdkaregrtciviahrlstiqnadlivviqngkvkehgthqqllaqk
giyfsmvsvqagakrshhhhhh

    Sequence, based on observed residues (ATOM records):
    >4m1mB (B:)
pavsvltmfryagwldrlymlvgtlaaiihgvalplmmlifgdmtdsfasvgqvskqstq
mseadkramfakleeemttyayyytgigagvlivayiqvsfwclaagrqihkirqkffha
imnqeigwfdvhdvgelntrltddvskinegigdkigmffqamatffggfiigftrgwkl
tlvilaispvlglsagiwakilssftdkelhayakagavaeevlaairtviafggqkkel
erynnnleeakrlgikkaitanismgaaflliyasyalafwygtslviskeysigqvltv
ffsvligafsvgqaspnieafanargaayevfkiidnkpsidsfsksghkpdniqgnlef
knihfsypsrkevqilkglnlkvksgqtvalvgnsgcgksttvqlmqrlydpldgmvsid
gqdirtinvrylreiigvvsqepvlfattiaenirygredvtmdeiekavkeanaydfim
klphqfdtlvgergaqlsggqkqriaiaralvrnpkillldeatsaldteseavvqaald
karegrttiviahrlstvrnadviagfdggviveqgnhdelmrekgiyfklvmtqtvppa
sfwrilklnstewpyfvvgifcaiingglqpafsvifskvvgvftnggppetqrqnsnlf
sllflilgiisfitfflqgftfgkageiltkrlrymvfksmlrqdvswfddpknttgalt
trlandaaqvkgatgsrlavifqnianlgtgiiisliygwqltllllaivpiiaiagvve
mkmlsgqalkdkkelegsgkiateaienfrtvvsltreqkfetmyaqslqipyrnamkka
hvfgitfsftqammyfsyaaafrfgaylvtqqlmtfenvllvfsaivfgamavgqvssfa
pdyakatvsashiiriiektpeidsystqglkpnmlegnvqfsgvvfnyptrpsipvlqg
lslevkkgqtlalvgssgcgkstvvqllerfydpmagsvfldgkeikqlnvqwlraqlgi
vsqepilfdcsiaeniaygdnsrvvsyeeivraakeanihqfidslpdkyntrvgdkgtq
lsggqkqriaiaralvrqphillldeatsaldtesekvvqealdkaregrtciviahrls
tiqnadlivviqngkvkehgthqqllaqkgiyfsmvsvqa