PDB entry 4m17

View 4m17 on RCSB PDB site
Description: Crystal Structure of Surfactant Protein-D D325A/R343V mutant
Class: sugar binding protein
Keywords: surfactant protein, carbohydrate recognition domain, lectin, SUGAR BINDING PROTEIN
Deposited on 2013-08-02, released 2013-12-04
The last revision prior to the SCOPe 2.03 freeze date was dated 2013-12-04, with a file datestamp of 2013-11-29.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.17
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Pulmonary surfactant-associated protein D
  Species: Homo sapiens [TaxId:9606]
  Gene: COLEC7, PSPD, SFTP4, SFTPD
  Database cross-references and differences (RAF-indexed):
  • Uniprot P35247 (Start-146)
    • engineered mutation (116)
    • engineered mutation (134)
• Chain 'B':
  Compound: Pulmonary surfactant-associated protein D
  Species: Homo sapiens [TaxId:9606]
  Gene: COLEC7, PSPD, SFTP4, SFTPD
  Database cross-references and differences (RAF-indexed):
  • Uniprot P35247 (Start-146)
    • engineered mutation (116)
    • engineered mutation (134)
• Chain 'C':
  Compound: Pulmonary surfactant-associated protein D
  Species: Homo sapiens [TaxId:9606]
  Gene: COLEC7, PSPD, SFTP4, SFTPD
  Database cross-references and differences (RAF-indexed):
  • Uniprot P35247 (Start-146)
    • engineered mutation (116)
    • engineered mutation (134)
• Chain 'D':
  Compound: Pulmonary surfactant-associated protein D
  Species: Homo sapiens [TaxId:9606]
  Gene: COLEC7, PSPD, SFTP4, SFTPD
  Database cross-references and differences (RAF-indexed):
  • Uniprot P35247 (Start-146)
    • engineered mutation (116)
    • engineered mutation (134)
  Domains in SCOPe 2.03: d4m17d1
• Chain 'E':
  Compound: Pulmonary surfactant-associated protein D
  Species: Homo sapiens [TaxId:9606]
  Gene: COLEC7, PSPD, SFTP4, SFTPD
  Database cross-references and differences (RAF-indexed):
  • Uniprot P35247 (Start-146)
    • engineered mutation (116)
    • engineered mutation (134)
  Domains in SCOPe 2.03: d4m17e1
• Chain 'F':
  Compound: Pulmonary surfactant-associated protein D
  Species: Homo sapiens [TaxId:9606]
  Gene: COLEC7, PSPD, SFTP4, SFTPD
  Database cross-references and differences (RAF-indexed):
  • Uniprot P35247 (Start-146)
    • engineered mutation (116)
    • engineered mutation (134)
  Domains in SCOPe 2.03: d4m17f1
• Chain 'G':
  Compound: Pulmonary surfactant-associated protein D
  Species: Homo sapiens [TaxId:9606]
  Gene: COLEC7, PSPD, SFTP4, SFTPD
  Database cross-references and differences (RAF-indexed):
  • Uniprot P35247 (Start-146)
    • engineered mutation (116)
    • engineered mutation (134)
• Chain 'H':
  Compound: Pulmonary surfactant-associated protein D
  Species: Homo sapiens [TaxId:9606]
  Gene: COLEC7, PSPD, SFTP4, SFTPD
  Database cross-references and differences (RAF-indexed):
  • Uniprot P35247 (Start-146)
    • engineered mutation (116)
    • engineered mutation (134)
• Chain 'I':
  Compound: Pulmonary surfactant-associated protein D
  Species: Homo sapiens [TaxId:9606]
  Gene: COLEC7, PSPD, SFTP4, SFTPD
  Database cross-references and differences (RAF-indexed):
  • Uniprot P35247 (Start-146)
    • engineered mutation (116)
    • engineered mutation (134)
• Chain 'J':
  Compound: Pulmonary surfactant-associated protein D
  Species: Homo sapiens [TaxId:9606]
  Gene: COLEC7, PSPD, SFTP4, SFTPD
  Database cross-references and differences (RAF-indexed):
  • Uniprot P35247 (Start-146)
    • engineered mutation (116)
    • engineered mutation (134)
• Chain 'K':
  Compound: Pulmonary surfactant-associated protein D
  Species: Homo sapiens [TaxId:9606]
  Gene: COLEC7, PSPD, SFTP4, SFTPD
  Database cross-references and differences (RAF-indexed):
  • Uniprot P35247 (Start-146)
    • engineered mutation (116)
    • engineered mutation (134)
• Chain 'L':
  Compound: Pulmonary surfactant-associated protein D
  Species: Homo sapiens [TaxId:9606]
  Gene: COLEC7, PSPD, SFTP4, SFTPD
  Database cross-references and differences (RAF-indexed):
  • Uniprot P35247 (Start-146)
    • engineered mutation (116)
    • engineered mutation (134)
• Heterogens: CA, HOH

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  No sequence available.
  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  Sequence, based on SEQRES records: (download)
  

  >4m17D (D:)
  qqvealqgqvqhlqaafsqykkvelfpngqsvgekifktagfvkpfteaqllctqaggql
  asprsaaenaalqqlvvakneaaflsmtdsktegkftyptgeslvysnwapgepndaggs
  edcveiftngkwndvacgekrlvvcef
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >4m17D (D:)
  gqvqhlqaafsqykkvelfpngqsvgekifktagfvkpfteaqllctqaggqlasprsaa
  enaalqqlvvakneaaflsmtdsktegkftyptgeslvysnwapgepndaggsedcveif
  tngkwndvacgekrlvvcef
  

  
  
• Chain 'E':
  Sequence, based on SEQRES records: (download)
  

  >4m17E (E:)
  qqvealqgqvqhlqaafsqykkvelfpngqsvgekifktagfvkpfteaqllctqaggql
  asprsaaenaalqqlvvakneaaflsmtdsktegkftyptgeslvysnwapgepndaggs
  edcveiftngkwndvacgekrlvvcef
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >4m17E (E:)
  gqvqhlqaafsqykkvelfpngqsvgekifktagfvkpfteaqllctqaggqlasprsaa
  enaalqqlvvakneaaflsmtdsktegkftyptgeslvysnwapgepndaggsedcveif
  tngkwndvacgekrlvvcef
  

  
  
• Chain 'F':
  Sequence, based on SEQRES records: (download)
  

  >4m17F (F:)
  qqvealqgqvqhlqaafsqykkvelfpngqsvgekifktagfvkpfteaqllctqaggql
  asprsaaenaalqqlvvakneaaflsmtdsktegkftyptgeslvysnwapgepndaggs
  edcveiftngkwndvacgekrlvvcef
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >4m17F (F:)
  qgqvqhlqaafsqykkvelfpngqsvgekifktagfvkpfteaqllctqaggqlasprsa
  aenaalqqlvvakneaaflsmtdsktegkftyptgeslvysnwapgepndaggsedcvei
  ftngkwndvacgekrlvvcef
  

  
  
• Chain 'G':
  No sequence available.
  
  
• Chain 'H':
  No sequence available.
  
  
• Chain 'I':
  No sequence available.
  
  
• Chain 'J':
  No sequence available.
  
  
• Chain 'K':
  No sequence available.
  
  
• Chain 'L':
  No sequence available.