PDB entry 4lzr
View 4lzr on RCSB PDB site
Description: Crystal Structure of BRD4(1) bound to Colchicine
Class: protein binding/inhibitor
Keywords: BRD4 inhibitor, bromodomain, epigenetic reader protein, acetylated lysine, histone tail, nucleus, PROTEIN BINDING-INHIBITOR complex
Deposited on
2013-08-01, released
2014-01-15
The last revision prior to the SCOPe 2.07 freeze date was dated
2014-01-29, with a file datestamp of
2014-01-24.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.206
AEROSPACI score: 0.4
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Bromodomain-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: BRD4, HUNK1
Database cross-references and differences (RAF-indexed):
- Uniprot O60885 (2-126)
- expression tag (0-1)
- conflict (22)
- conflict (74)
- conflict (113)
Domains in SCOPe 2.07: d4lzra1, d4lzra2 - Heterogens: LOC, HOH