PDB entry 4lz7

View 4lz7 on RCSB PDB site
Description: Crystal structures of GLuR2 ligand-binding-domain in complex with glutamate and positive allosteric modulators
Class: transport protein
Keywords: AMPA receptor, allosteric modulator, TRANSPORT PROTEIN
Deposited on 2013-07-31, released 2013-12-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-07-26, with a file datestamp of 2017-07-21.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Gria2, Glur2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (Start-128)
    • Uniprot P19491 (131-End)
      • linker (129-130)
    Domains in SCOPe 2.08: d4lz7a_
  • Chain 'B':
    Compound: Glutamate receptor 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Gria2, Glur2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (Start-128)
    • Uniprot P19491 (131-End)
      • linker (129-130)
    Domains in SCOPe 2.08: d4lz7b_
  • Chain 'C':
    Compound: Glutamate receptor 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Gria2, Glur2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (Start-128)
    • Uniprot P19491 (131-End)
      • linker (129-130)
    Domains in SCOPe 2.08: d4lz7c_
  • Heterogens: ZN, GLU, 1YW, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4lz7A (A:)
gsamgsgndtsrganktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcg
fkykltivgdgkygardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfms
lgisimikkgtpiesaedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaeps
vfvrttaegvarvrkskgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgs
slgnavnlavlklneqglldklknkwwydkgecgs

    Sequence, based on observed residues (ATOM records): (download) 
    >4lz7A (A:)
ktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyga
rdadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpies
aedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrk
skgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlklne
qglldklknkwwydkgec

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4lz7B (B:)
gsamgsgndtsrganktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcg
fkykltivgdgkygardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfms
lgisimikkgtpiesaedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaeps
vfvrttaegvarvrkskgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgs
slgnavnlavlklneqglldklknkwwydkgecgs

    Sequence, based on observed residues (ATOM records): (download) 
    >4lz7B (B:)
tvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkygar
dadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpiesa
edlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrks
kgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlklneq
glldklknkwwydkgec

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4lz7C (C:)
gsamgsgndtsrganktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcg
fkykltivgdgkygardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfms
lgisimikkgtpiesaedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaeps
vfvrttaegvarvrkskgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgs
slgnavnlavlklneqglldklknkwwydkgecgs

    Sequence, based on observed residues (ATOM records): (download) 
    >4lz7C (C:)
tvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkygar
dadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpiesa
edlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrks
kgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlklneq
glldklknkwwydkgec