PDB entry 4lyw
View 4lyw on RCSB PDB site
Description: Crystal Structure of BRD4(1) bound to inhibitor XD14
Class: protein binding/inhibitor
Keywords: BRD4 inhibitor, bromodomain, epigenetic reader protein, acetylated lysine, histone tail, PROTEIN BINDING-INHIBITOR complex
Deposited on
2013-07-31, released
2014-01-15
The last revision prior to the SCOPe 2.07 freeze date was dated
2014-01-15, with a file datestamp of
2014-01-10.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.199
AEROSPACI score: 0.38
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Bromodomain-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: BRD4, HUNK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d4lywa1, d4lywa2 - Heterogens: 21Q, HOH