PDB entry 4lxs

View 4lxs on RCSB PDB site
Description: structure of the toll - spatzle complex, a molecular hub in drosophila development and innate immunity (glycosylated form)
Deposited on 2013-07-30, released 2014-04-09
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein toll
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Tl, CG5490
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: protein spaetzle c-106
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: spz, CG6134
    Database cross-references and differences (RAF-indexed):
    • Uniprot P48607 (Start-105)
      • expression tag (106-108)
  • Chain 'K':
    Compound: protein spaetzle c-106
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: spz, CG6134
    Database cross-references and differences (RAF-indexed):
    • Uniprot P48607 (0-105)
      • expression tag (106)
  • Heterogens: NAG, EPE

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4lxsA (A:)
sfgrdacsemsidglcqcapimseyeiicpanaenptfrltiqpkdyvqimcnltdttdy
qqlpkklrigevdrvqmrrcmlpghtpiasildylgivspttlifesdnlgmnitrqhld
rlhglkrfrfttrrlthipanlltdmrnlshlelranieempshlfddlenlesiefgsn
klrqmprgifgkmpklkqlnlwsnqlhnltkhdfegatsvlgidihdngieqlphdvfah
ltnvtdinlsanlfrslpqglfdhnkhlnevrlmnnrvplatlpsrlfanqpelqilrlr
aelqslpgdlfehstqitnislgdnllktlpatllehqvnllsldlsnnrlthlpdslfa
httnltdlrlednlltgisgdifsnlgnlvtlvmsrnrlrtidsrafvstnglrhlhldh
ndidlqqplldimlqtqinspfgymhglltlnlrnnsiifvyndwkntmlqlreldlsyn
nisslgyedlaflsqnrlhvnmthnkirrialpedvhlgegynnnlvhvdlndnplvcdc
tilwfiqlvrgvhkpqysrqfklrtdrlvcsqpnvlegtpvrqiepqtlicpldfsddpr
erkcprgcnchvrtydkalvinchsgnlthvprlpnlhknmqlmelhlenntllrlpsan
tpgyesvtslhlagnnltsidvdqlptnlthldiswnhlqmlnatvlgflnrtmkwrsvk
lsgnpwmcdctakplllftqdnferigdrnemmcvnaemptrmvelstndicpaetghhh
hhh

    Sequence, based on observed residues (ATOM records):
    >4lxsA (A:)
sfgrdacsedglcqcapimseyeiicpanaenptfrltiqpkdyvqimcnltdttdyqql
pkklrigevdrvqmrrcmlpghtpiasildylgivspttlifesdnlgmnitrqhldrlh
glkrfrfttrrlthipanlltdmrnlshlelranieempshlfddlenlesiefgsnklr
qmprgifgkmpklkqlnlwsnqlhnltkhdfegatsvlgidihdngieqlphdvfahltn
vtdinlsanlfrslpqglfdhnkhlnevrlmnnrvplatlpsrlfanqpelqilrlrael
qslpgdlfehstqitnislgdnllktlpatllehqvnllsldlsnnrlthlpdslfahtt
nltdlrlednlltgisgdifsnlgnlvtlvmsrnrlrtidsrafvstnglrhlhldhndi
dlqqplldimlqtqinspfgymhglltlnlrnnsiifvyndwkntmlqlreldlsynnis
slgyedlaflsqnrlhvnmthnkirrialpedvlvhvdlndnplvcdctilwfiqlvrgv
hkpqysrqfklrtdrlvcsqpnvlegtpvrqiepqtlicpldkcprgcnchvrtydkalv
inchsgnlthvprlpnlhknmqlmelhlenntllrlpsantpgyesvtslhlagnnltsi
dvdqlptnlthldiswnhlqmlnatvlgflnwrsvklsgnpwmcdctakplllftqdnfe
rigdrnemmcvnaptrmvelstndicp

  • Chain 'J':
    Sequence, based on SEQRES records:
    >4lxsJ (J:)
vggsderflcrsirklvypkkglraddtwqlivnndeykqaiqieecegadqpcdfaanf
pqsynpickqhytqqtlasiksdgeldvvqnsfkipscckcalktglehhhhhh

    Sequence, based on observed residues (ATOM records):
    >4lxsJ (J:)
derflcrsirklvyiqieecegadqpcdfaanfpqsynpickqhytqkipscckcalktg
leh

  • Chain 'K':
    Sequence, based on SEQRES records:
    >4lxsK (K:)
vggsderflcrsirklvypkkglraddtwqlivnndeykqaiqieecegadqpcdfaanf
pqsynpickqhytqqtlasiksdgeldvvqnsfkipscckcalktglehhhhhh

    Sequence, based on observed residues (ATOM records):
    >4lxsK (K:)
vggsderflcrsirklkqaiqieecegadqpcdfaanfpqsynpickqhytkipscckca
lktgl