PDB entry 4lxl

View 4lxl on RCSB PDB site
Description: Crystal structure of JMJD2B complexed with pyridine-2,4-dicarboxylic acid and H3K9me3
Deposited on 2013-07-30, released 2014-07-30
The last revision was dated 2014-07-30, with a file datestamp of 2014-07-25.
Experiment type: XRAY
Resolution: 1.87 Å
R-factor: 0.179
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lysine-specific demethylase 4B
    Species: Homo sapiens [TaxId:9606]
    Gene: KDM4B
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: H3 peptide
    Species: human, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LXL (0-7)
  • Heterogens: PD2, NI, ZN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4lxlA (A:)
mgsshhhhhhssglvprgshmgsedhgaqnpsckimtfrptmeefkdfnkyvayiesqga
hraglakiippkewkprqtyddiddvvipapiqqvvtgqsglftqyniqkkamtvgeyrr
lansekyctprhqdfddlerkywknltfvspiygadisgslydddvaqwnigslrtildm
verecgtiiegvntpylyfgmwkttfawhtedmdlysinylhfgepkswyaippehgkrl
erlaigffpgssqgcdaflrhkmtlispiilkkygipfsritqeagefmitfpygyhagf
nhgfncaestnfatlrwidygkvatqctcrkdmvkismdvfvrilqperyelwkqgkdlt
vldhtrpt

    Sequence, based on observed residues (ATOM records):
    >4lxlA (A:)
qnpsckimtfrptmeefkdfnkyvayiesqgahraglakiippkewkprqtyddiddvvi
papiqqvvtgqsglftqyniqkkamtvgeyrrlansekyctprhqdfddlerkywknltf
vspiygadisgslydddvaqwnigslrtildmverecgtiiegvntpylyfgmwkttfaw
htedmdlysinylhfgepkswyaippehgkrlerlaigffpgssqgcdaflrhkmtlisp
iilkkygipfsritqeagefmitfpygyhagfnhgfncaestnfatlrwidygkvatqct
crkdmvkismdvfvrilqperyelwkqgk

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >4lxlD (D:)
arkstggk