PDB entry 4lxd

View 4lxd on RCSB PDB site
Description: Bcl_2-Navitoclax Analog (without Thiophenyl) Complex
Class: apoptosis regulator/inhibitor
Keywords: 8 helices, APOPTOSIS REGULATOR-INHIBITOR complex
Deposited on 2013-07-29, released 2013-08-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-08-02, with a file datestamp of 2017-07-28.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Apoptosis regulator Bcl-2
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4lxda_
  • Heterogens: 1XV, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4lxdA (A:)
mahpgrtgydnreivmkyihyklsqrgyewdagddveenrteapegtesevvhltlrqag
ddfsrryrrdfaemssqlhltpftargrfatvveelfrdgvnwgrivaffefggvmcves
vnremsplvdnialwmteylnrhlhtwiqdnggwdafvelygpsmr

    Sequence, based on observed residues (ATOM records): (download) 
    >4lxdA (A:)
rtgydnreivmkyihyklsqrgyewdagsevvhltlrqagddfsrryrrdfaemssqlhl
tpftargrfatvveelfrdgvnwgrivaffefggvmcvesvnremsplvdnialwmteyl
nrhlhtwiqdnggwdafvelygp