PDB entry 4lwb

View 4lwb on RCSB PDB site
Description: Structure of Bacillus subtilis nitric oxide synthase in complex with 6-((((3R,5S)-5-(((6-amino-4-methylpyridin-2-yl)methoxy)methyl)pyrrolidin-3-yl)oxy)methyl)-4-methylpyridin-2-amine
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: nitric oxide synthase, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Deposited on 2013-07-26, released 2013-10-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nitric oxide synthase oxygenase
    Species: Bacillus subtilis subsp. subtilis [TaxId:224308]
    Gene: BSU07630, nos, yflM
    Database cross-references and differences (RAF-indexed):
    • Uniprot O34453 (Start-362)
      • engineered mutation (24-25)
      • engineered mutation (315)
    Domains in SCOPe 2.08: d4lwba_
  • Heterogens: HEM, QJ8, H4B, CL, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4lwbA (A:)
meekeilwneakafiaacyqelgkaaevkdrladikseidltgsyvhtkeelehgakmaw
rnsnrcigrlfwnslnvidrrdvrtkeevrdalfhhietatnngkirptitifppeekge
kqveiwnhqliryagyesdgerigdpascsltaaceelgwrgertdfdllplifrmkgde
qpvwyelprslvievpithpdieafsdlelkwygvpiisdmklevggihynaapfngwym
gteigarnladekrydklkkvasvigiaadyntdlwkdqalvelnkavlhsykkqgvsiv
dhhtaasqfkrfeeqaeeagrkltgdwtwlippispaathifhrsydnsivkpnyfyqdk
pye

    Sequence, based on observed residues (ATOM records): (download) 
    >4lwbA (A:)
eekeilwneakafiaacyqelgkaaevkdrladikseidltgsyvhtkeelehgakmawr
nsnrcigrlfwnslnvidrrdvrtkeevrdalfhhietatnngkirptitifppeekgek
qveiwnhqliryagyesdgerigdpascsltaaceelgwrgertdfdllplifrmkgdeq
pvwyelprslvievpithpdieafsdlelkwygvpiisdmklevggihynaapfngwymg
teigarnladekrydklkkvasvigiaadyntdlwkdqalvelnkavlhsykkqgvsivd
hhtaasqfkrfeeqaeeagrkltgdwtwlippispaathifhrsydnsivkpnyfyqdkp
ye