PDB entry 4lw4

View 4lw4 on RCSB PDB site
Description: Structural changes during cysteine desulfurase CsdA and sulfur-acceptor CsdE interactions provide insight into the trans-persulfuration
Class: lyase
Keywords: cysteine desulfurase, CsdA, SufE, LYASE
Deposited on 2013-07-26, released 2013-08-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-08-21, with a file datestamp of 2013-08-16.
Experiment type: XRAY
Resolution: 2.01 Å
R-factor: 0.162
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cysteine sulfinate desulfinase
    Species: Escherichia coli [TaxId:83333]
    Gene: b2810, csdA, JW2781, ygdJ
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4lw4a_
  • Chain 'B':
    Compound: Cysteine sulfinate desulfinase
    Species: Escherichia coli [TaxId:83333]
    Gene: b2810, csdA, JW2781, ygdJ
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4lw4b_
  • Chain 'C':
    Compound: Cysteine desulfuration protein CsdE
    Species: Escherichia coli [TaxId:714962]
    Gene: csdE, ECOK1_3187
    Database cross-references and differences (RAF-indexed):
    • Uniprot D5CZ88 (Start-149)
      • engineered mutation (51)
    Domains in SCOPe 2.08: d4lw4c_
  • Chain 'D':
    Compound: Cysteine desulfuration protein CsdE
    Species: Escherichia coli [TaxId:714962]
    Gene: csdE, ECOK1_3187
    Database cross-references and differences (RAF-indexed):
    • Uniprot D5CZ88
      • engineered mutation (51)
    Domains in SCOPe 2.08: d4lw4d_
  • Heterogens: PLP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4lw4A (A:)
gshmnvfnpaqfraqfpalqdagvyldsaatalkpeavveatqqfyslsagnvhrsqfae
aqrltaryeaarekvaqllnapddktivwtrgttesinmvaqcyarprlqpgdeiivsva
ehhanlvpwlmvaqqtgakvvklplnaqrlpdvdllpelitprsrilalgqmsnvtggcp
dlaraitfahsagmvvmvdgaqgavhfpadvqqldidfyafsghklygptgigvlygkse
lleamspwlgggkmvhevsfdgfttqsapwkleagtpnvagviglsaalewladydinqa
eswsrslatlaedalakrpgfrsfrcqdssllafdfagvhhsdmvtllaeygialragqh
caqpllaelgvtgtlrasfapyntksdvdalvnavdralellvd

    Sequence, based on observed residues (ATOM records): (download) 
    >4lw4A (A:)
vfnpaqfraqfpalqdagvyldsaatalkpeavveatqqfyslsagfaeaqrltaryeaa
rekvaqllnapddktivwtrgttesinmvaqcyarprlqpgdeiivsvaehhanlvpwlm
vaqqtgakvvklplnaqrlpdvdllpelitprsrilalgqmsnvtggcpdlaraitfahs
agmvvmvdgaqgavhfpadvqqldidfyafsghklygptgigvlygkselleamspwlgg
gkmvhevsfdgfttqsapwkleagtpnvagviglsaalewladydinqaeswsrslatla
edalakrpgfrsfrcqdssllafdfagvhhsdmvtllaeygialragqhcaqpllaelgv
tgtlrasfapyntksdvdalvnavdralellv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4lw4B (B:)
gshmnvfnpaqfraqfpalqdagvyldsaatalkpeavveatqqfyslsagnvhrsqfae
aqrltaryeaarekvaqllnapddktivwtrgttesinmvaqcyarprlqpgdeiivsva
ehhanlvpwlmvaqqtgakvvklplnaqrlpdvdllpelitprsrilalgqmsnvtggcp
dlaraitfahsagmvvmvdgaqgavhfpadvqqldidfyafsghklygptgigvlygkse
lleamspwlgggkmvhevsfdgfttqsapwkleagtpnvagviglsaalewladydinqa
eswsrslatlaedalakrpgfrsfrcqdssllafdfagvhhsdmvtllaeygialragqh
caqpllaelgvtgtlrasfapyntksdvdalvnavdralellvd

    Sequence, based on observed residues (ATOM records): (download) 
    >4lw4B (B:)
vfnpaqfraqfpalqdagvyldsaatalkpeavveatqqfyslsagnvhrsqfaeaqrlt
aryeaarekvaqllnapddktivwtrgttesinmvaqcyarprlqpgdeiivsvaehhan
lvpwlmvaqqtgakvvklplnaqrlpdvdllpelitprsrilalgqmsnvtggcpdlara
itfahsagmvvmvdgaqgavhfpadvqqldidfyafsghklygptgigvlygkselleam
spwlgggkmvhevsfdgfttqsapwkleagtpnvagviglsaalewladydinqaeswsr
slatlaedalakrpgfrsfrcqdssllafdfagvhhsdmvtllaeygialragqhcaqpl
laelgvtgtlrasfapyntksdvdalvnavdralellv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4lw4C (C:)
gshmtnpqfaghpfgttvtaetlrntfapltqwedkyrqlimlgkqlpalpdelkaqake
iagcenrvwlgytvaengkmhffgdsegrivrgllavlltavegktaaelqaqsplalfd
elglraqlsasrsqglnalseaiiaaakqv

    Sequence, based on observed residues (ATOM records): (download) 
    >4lw4C (C:)
npqfaghpfgttvtaetlrntfapltqwedkyrqlimlgkqlpalpdelkaqakeiagce
nrvwlgytvaengkmhffgdsegrivrgllavlltavegktaaelqaqsplalfdelglr
aqlsasrsqglnalseaiiaaakqv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4lw4D (D:)
gshmtnpqfaghpfgttvtaetlrntfapltqwedkyrqlimlgkqlpalpdelkaqake
iagcenrvwlgytvaengkmhffgdsegrivrgllavlltavegktaaelqaqsplalfd
elglraqlsasrsqglnalseaiiaaakqv

    Sequence, based on observed residues (ATOM records): (download) 
    >4lw4D (D:)
ghpfgttvtaetlrntfapltqwedkyrqlimlgkqlpalpdelkaqakeiagenrvwlg
ytvaengkmhffgdsegrivrgllavlltavegktaaelqaqsplalfdelglraqlsas
rsqglnalseaiiaaak