PDB entry 4lw1
View 4lw1 on RCSB PDB site
Description: Fragment-Based Discovery of a Potent Inhibitor of Replication Protein A Protein-Protein Interactions
Class: DNA BINDING protein/inhibitor
Keywords: OB-FOLD, PROTEIN-PROTEIN INTERACTION, DNA BINDING protein-inhibitor complex
Deposited on
2013-07-26, released
2013-12-11
The last revision prior to the SCOPe 2.08 freeze date was dated
2014-12-10, with a file datestamp of
2014-12-05.
Experiment type: XRAY
Resolution: 1.63 Å
R-factor: 0.18
AEROSPACI score: 0.49
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Replication protein A 70 kDa DNA-binding subunit
Species: Homo sapiens [TaxId:9606]
Gene: RPA1, REPA1, RPA70
Database cross-references and differences (RAF-indexed):
- Uniprot P27694 (3-122)
- expression tag (0-2)
- engineered mutation (9)
Domains in SCOPe 2.08: d4lw1a1, d4lw1a2 - Heterogens: 1XS, HOH