PDB entry 4lu5

View 4lu5 on RCSB PDB site
Description: Structure of murine IgG2a A20G2-Fab in complex with vaccinia antigen A33R at the resolution of 2.9 Angstroms
Class: immune system
Keywords: IgG domain, antibody-antigen complex, Fv, CH1, IgG2a, antigen-binding fragment (Fab), A33R antigen, Papain digest of the mAb, EEV membrane (outer membrane of vaccinia EV form), IMMUNE SYSTEM
Deposited on 2013-07-24, released 2014-07-30
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-07-30, with a file datestamp of 2014-07-25.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.237
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: a33r
  Species: Vaccinia virus [TaxId:10245]
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q71TT1 (Start-96)
    • engineered mutation (29)
    • engineered mutation (34)
    • engineered mutation (51)
• Chain 'B':
  Compound: a33r
  Species: Vaccinia virus [TaxId:10245]
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q71TT1 (Start-96)
    • engineered mutation (29)
    • engineered mutation (34)
    • engineered mutation (51)
• Chain 'H':
  Compound: Murine IgG2a A20G2 Heavy chain Fab domain
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • PDB 4LU5 (0-212)
• Chain 'I':
  Compound: Murine IgG2a A20G2 Heavy chain Fab domain
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • PDB 4LU5 (0-212)
• Chain 'L':
  Compound: Murine IgG2a A20G2 Light chain Fab domain
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • PDB 4LU5 (0-218)
  Domains in SCOPe 2.05: d4lu5l1, d4lu5l2
• Chain 'M':
  Compound: Murine IgG2a A20G2 Light chain Fab domain
  Species: Mus musculus [TaxId:10090]
  Database cross-references and differences (RAF-indexed):
  • PDB 4LU5 (0-218)
  Domains in SCOPe 2.05: d4lu5m1, d4lu5m2
• Heterogens: HOH

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  No sequence available.
  
  
• Chain 'H':
  No sequence available.
  
  
• Chain 'I':
  No sequence available.
  
  
• Chain 'L':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4lu5L (L:)
  dvvmtqtpltlsvtigqpasisckssqsllysngktylnwllqrpgqspkrliylvskld
  sgvpdrftgsgsgtdftlkisrveaedlgiyycvqgthfpytfgggtkleikradaaptv
  sifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysm
  sstltltkdeyerhnsytceathktstspivksfnrnec
  

  
  
• Chain 'M':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4lu5M (M:)
  dvvmtqtpltlsvtigqpasisckssqsllysngktylnwllqrpgqspkrliylvskld
  sgvpdrftgsgsgtdftlkisrveaedlgiyycvqgthfpytfgggtkleikradaaptv
  sifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysm
  sstltltkdeyerhnsytceathktstspivksfnrnec