PDB entry 4lsz

View 4lsz on RCSB PDB site
Description: caspase-7 in complex with darpin d7.18
Deposited on 2013-07-23, released 2014-07-02
The last revision was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 2.26 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: caspase-7 subunit p20
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP7, MCH3
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Caspase-7 subunit p10
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP7, MCH3
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: caspase-7 subunit p20
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP7, MCH3
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Caspase-7 subunit p10
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP7, MCH3
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: DARPin D7.18
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LSZ
  • Chain 'F':
    Compound: DARPin D7.18
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LSZ
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4lszA (A:)
akpdrssfvpslfskkkknvtmrsikttrdrvptyqynmnfeklgkciiinnknfdkvtg
mgvrngtdkdaealfkcfrslgfdvivyndcscakmqdllkkaseedhtnaacfacills
hgeenviygkdgvtpikdltahfrgdrcktllekpklffiqacrgtelddgiqad

    Sequence, based on observed residues (ATOM records):
    >4lszA (A:)
yqynmnfeklgkciiinnknfdkvtgmgvrngtdkdaealfkcfrslgfdvivyndcsca
kmqdllkkaseedhtnaacfacillshgeenviygkdgvtpikdltahfrgdrcktllek
pklffiqacrgtelddgiqa

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4lszB (B:)
anprykipveadflfaystvpgyyswrspgrgswfvqalcsileehgkdleimqiltrvn
drvarhfesqsddphfhekkqipcvvsmltkelyfsqlehhhhhh

    Sequence, based on observed residues (ATOM records):
    >4lszB (B:)
rykipveadflfaystvpgyyswrspgrgswfvqalcsileehgkdleimqiltrvndrv
arhfesqsddphfhekkqipcvvsmltkelyfsq

  • Chain 'C':
    Sequence, based on SEQRES records:
    >4lszC (C:)
akpdrssfvpslfskkkknvtmrsikttrdrvptyqynmnfeklgkciiinnknfdkvtg
mgvrngtdkdaealfkcfrslgfdvivyndcscakmqdllkkaseedhtnaacfacills
hgeenviygkdgvtpikdltahfrgdrcktllekpklffiqacrgtelddgiqad

    Sequence, based on observed residues (ATOM records):
    >4lszC (C:)
yqynmnfeklgkciiinnknfdkvtgmgvrngtdkdaealfkcfrslgfdvivyndcsca
kmqdllkkaseedhtnaacfacillshgeenviygkdgvtpikdltahfrgdrcktllek
pklffiqacrgtelddgiqad

  • Chain 'D':
    Sequence, based on SEQRES records:
    >4lszD (D:)
anprykipveadflfaystvpgyyswrspgrgswfvqalcsileehgkdleimqiltrvn
drvarhfesqsddphfhekkqipcvvsmltkelyfsqlehhhhhh

    Sequence, based on observed residues (ATOM records):
    >4lszD (D:)
prykipveadflfaystvpgyyswrspgrgswfvqalcsileehgkdleimqiltrvndr
varhfesqsddphfhekkqipcvvsmltkelyfsq

  • Chain 'E':
    Sequence, based on SEQRES records:
    >4lszE (E:)
mrgshhhhhhgsdlgkklleaaragqddevrilmangadvnaddawgqtplhlaaqnghl
eivevllkhdadvnatdwvgmtplhlaaddghleiveallkygadvnaydqlgntplnla
atdghleivevllkygadvnaqdkfgktafdisidngnedlaeilqkln

    Sequence, based on observed residues (ATOM records):
    >4lszE (E:)
sdlgkklleaaragqddevrilmangadvnaddawgqtplhlaaqnghleivevllkhda
dvnatdwvgmtplhlaaddghleiveallkygadvnaydqlgntplnlaatdghleivev
llkygadvnaqdkfgktafdisidngnedlaei

  • Chain 'F':
    Sequence, based on SEQRES records:
    >4lszF (F:)
mrgshhhhhhgsdlgkklleaaragqddevrilmangadvnaddawgqtplhlaaqnghl
eivevllkhdadvnatdwvgmtplhlaaddghleiveallkygadvnaydqlgntplnla
atdghleivevllkygadvnaqdkfgktafdisidngnedlaeilqkln

    Sequence, based on observed residues (ATOM records):
    >4lszF (F:)
dlgkklleaaragqddevrilmangadvnaddawgqtplhlaaqnghleivevllkhdad
vnatdwvgmtplhlaaddghleiveallkygadvnaydqlgntplnlaatdghleivevl
lkygadvnaqdkfgktafdisidngnedlaeilq