PDB entry 4lsu

View 4lsu on RCSB PDB site
Description: Crystal structure of broadly and potently neutralizing antibody VRC-PG20 in complex with HIV-1 clade A/E 93TH057 gp120
Class: viral protein/immune system
Keywords: Neutralizing antibody VRC-PG20, viral protein-immune system complex
Deposited on 2013-07-23, released 2013-08-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'G':
    Compound: hiv-1 clade a/e strain 93th057 gp120
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: ENV
    Database cross-references and differences (RAF-indexed):
    • PDB 4LSU (0-352)
  • Chain 'H':
    Compound: heavy chain of antibody vrc-pg20
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LSU (0-End)
    Domains in SCOPe 2.08: d4lsuh_
  • Chain 'L':
    Compound: light chain of antibody vrc-pg20
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LSU (Start-203)
    Domains in SCOPe 2.08: d4lsul1, d4lsul2
  • Heterogens: NAG, EPE, EDO, CL, HOH

PDB Chain Sequences:

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4lsuH (H:)
evhlmqsgtemkkpgasvrvtcqtsgytfsdyfihwlrqvpgrgfewmgwmnpqwgqvny
artfqgrvtmtrdvyrevayldlrsltfadtavyfcarrmrsqdrewdfqhwgqgtriiv
ssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlq
ssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdk

    Sequence, based on observed residues (ATOM records): (download) 
    >4lsuH (H:)
evhlmqsgtemkkpgasvrvtcqtsgytfsdyfihwlrqvpgrgfewmgwmnpqwgqvny
artfqgrvtmtrdvyrevayldlrsltfadtavyfcarrmrsqdrewdfqhwgqgtriiv
ssastkgpsvfplapsssggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >4lsuL (L:)
qsaltqppsvsgspgqsitlsctgastsvawyqqyadkaprlivfdgnkrpsdissrfsg
sqsggtasltisglqsedeayyhcnafeffgggtkltvlsqpkaapsvtlfppsseelqa
nkatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassylsltpeqwks
hksyscqvthegstvektvaptec

    Sequence, based on observed residues (ATOM records): (download) 
    >4lsuL (L:)
saltqppsvsgspgqsitlsctgastsvawyqqyadkaprlivfdgnkrpsdissrfsgs
qsggtasltisglqsedeayyhcnafeffgggtkltvlsqpkaapsvtlfppsseelqan
katlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassylsltpeqwksh
ksyscqvthegstvektvaptec