PDB entry 4lsj

View 4lsj on RCSB PDB site
Description: Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Bound to a Dibenzoxapine Sulfonamide
Deposited on 2013-07-22, released 2014-01-29
The last revision was dated 2014-03-12, with a file datestamp of 2014-03-07.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.185
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glucocorticoid receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: NR3C1, GRL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04150 (Start-257)
      • engineered mutation (82)
      • engineered mutation (118)
  • Chain 'B':
    Compound: D30 peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 4LSJ
  • Heterogens: LSJ, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4lsjA (A:)
slpatlpqltptlvslleviepevlyagydssvpdstwrimttlnmlggrqviaavkwak
aipgfrnlhlddqmtllqyswmylmafalgwrsyrqssanllcfapdliineqrmtlpgm
ydqckhmlyvsselhrlqvsyeeylcmktllllssvpkdglksqelfdeirmtyikelgk
aivkregnssqnwqrfyqltklldsmhevvenllnycfqtfldktmsiefpemlaeiitn
qipkysngnikkllfhqk

    Sequence, based on observed residues (ATOM records):
    >4lsjA (A:)
pqltptlvslleviepevlyagydssvpdstwrimttlnmlggrqviaavkwakaipgfr
nlhlddqmtllqyswmylmafalgwrsyrqssanllcfapdliineqrmtlpgmydqckh
mlyvsselhrlqvsyeeylcmktllllssvpkdglksqelfdeirmtyikelgkaivnwq
rfyqltklldsmhevvenllnycfqtfldktmsiefpemlaeiitnqipkysngnikkll
fhqk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4lsjB (B:)
hssrlwellmeat

    Sequence, based on observed residues (ATOM records):
    >4lsjB (B:)
ssrlwellme