PDB entry 4lrl

View 4lrl on RCSB PDB site
Description: Structure of an Enterococcus Faecalis HD-domain protein complexed with dGTP and dTTP
Class: hydrolase
Keywords: Structural Genomics, PSI-2, Protein Structure Initiative, Midwest Center for Structural Genomics, MCSG, HD Domain, Phosphohydrolase, dNTPase, Allosteric Regulation, METAL BINDING PROTEIN, HYDROLASE
Deposited on 2013-07-19, released 2013-11-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HD domain protein
    Species: Enterococcus faecalis [TaxId:226185]
    Gene: EF-1143, EF_1143
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q836G9 (24-479)
      • expression tag (23)
    Domains in SCOPe 2.08: d4lrla1, d4lrla2
  • Chain 'B':
    Compound: HD domain protein
    Species: Enterococcus faecalis [TaxId:226185]
    Gene: EF-1143, EF_1143
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4lrlb_
  • Chain 'C':
    Compound: HD domain protein
    Species: Enterococcus faecalis [TaxId:226185]
    Gene: EF-1143, EF_1143
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4lrlc_
  • Chain 'D':
    Compound: HD domain protein
    Species: Enterococcus faecalis [TaxId:226185]
    Gene: EF-1143, EF_1143
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4lrld_
  • Heterogens: NI, DGT, TRS, TTP, MLI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4lrlA (A:)
mhhhhhhssgvdlgtenlyfqsnamtipykeqrlpiekvfrdpvhnyihvqhqvildlin
saevqrlrrikqlgtssftfhgaehsrfshslgvyeitrriceifqrnysverlgengwn
dderlitlcaallhdvghgpyshtfehifdtnheaitvqiitspetevyqilnrvsadfp
ekvasvitkqypnpqvvqmissqidadrmdyllrdayftgteygtfdltrilrvirpykg
giafamngmhavedyivsryqmyvqvyfhpvsrgmevildhllhrakelfenpefdydlq
asllvpffkgdftlqeylklddgvlstyftqwmdvpdsilgdlakrflmrkplksatftn
ekesaatiaylreliekvgfnpkyytainssydlpydfyrpnkdrhrtqielmqkdgslv
elatvsplvaalagqsqgderfyfpkemldqgnkkhydlfdetyrefssyihngalvlkk

    Sequence, based on observed residues (ATOM records): (download) 
    >4lrlA (A:)
amtipykeqrlpiekvfrdpvhnyihvqhqvildlinsaevqrlrrikqlgtssftfhga
ehsrfshslgvyeitrriceifqrnysverlgengwndderlitlcaallhdvghgpysh
tfehifdtnheaitvqiitspetevyqilnrvsadfpekvasvitkqypnpqvvqmissq
idadrmdyllrdayftgteygtfdltrilrvirpykggiafamngmhavedyivsryqmy
vqvyfhpvsrgmevildhllhrakelfenpefdydlqasllvpffkgdftlqeylklddg
vlstyftqwmdvpdsilgdlakrflmrkplksatftnekesaatiaylreliekvgfnpk
yytainssydlpydfyrpnkdrhrtqielmqkdgslvelatvsplvaalagqsqgderfy
fpkemldqdlfdetyrefssyihngalvlkk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4lrlB (B:)
mhhhhhhssgvdlgtenlyfqsnamtipykeqrlpiekvfrdpvhnyihvqhqvildlin
saevqrlrrikqlgtssftfhgaehsrfshslgvyeitrriceifqrnysverlgengwn
dderlitlcaallhdvghgpyshtfehifdtnheaitvqiitspetevyqilnrvsadfp
ekvasvitkqypnpqvvqmissqidadrmdyllrdayftgteygtfdltrilrvirpykg
giafamngmhavedyivsryqmyvqvyfhpvsrgmevildhllhrakelfenpefdydlq
asllvpffkgdftlqeylklddgvlstyftqwmdvpdsilgdlakrflmrkplksatftn
ekesaatiaylreliekvgfnpkyytainssydlpydfyrpnkdrhrtqielmqkdgslv
elatvsplvaalagqsqgderfyfpkemldqgnkkhydlfdetyrefssyihngalvlkk

    Sequence, based on observed residues (ATOM records): (download) 
    >4lrlB (B:)
tipykeqrlpiekvfrdpvhnyihvqhqvildlinsaevqrlrrikqlgtssftfhgaeh
srfshslgvyeitrriceifqrnysverlgengwndderlitlcaallhdvghgpyshtf
ehifdtnheaitvqiitspetevyqilnrvsadfpekvasvitkqypnpqvvqmissqid
adrmdyllrdayftgteygtfdltrilrvirpykggiafamngmhavedyivsryqmyvq
vyfhpvsrgmevildhllhrakelfenpefdydlqasllvpffkgdftlqeylklddgvl
styftqwmdvpdsilgdlakrflmrkplksatftnekesaatiaylreliekvgfnpkyy
tainssydlpydfyrprhrtqielmqkdgslvelatvsplvaalagqsqgderfyfpkem
lddlfdetyrefssyihngalvlkk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4lrlC (C:)
mhhhhhhssgvdlgtenlyfqsnamtipykeqrlpiekvfrdpvhnyihvqhqvildlin
saevqrlrrikqlgtssftfhgaehsrfshslgvyeitrriceifqrnysverlgengwn
dderlitlcaallhdvghgpyshtfehifdtnheaitvqiitspetevyqilnrvsadfp
ekvasvitkqypnpqvvqmissqidadrmdyllrdayftgteygtfdltrilrvirpykg
giafamngmhavedyivsryqmyvqvyfhpvsrgmevildhllhrakelfenpefdydlq
asllvpffkgdftlqeylklddgvlstyftqwmdvpdsilgdlakrflmrkplksatftn
ekesaatiaylreliekvgfnpkyytainssydlpydfyrpnkdrhrtqielmqkdgslv
elatvsplvaalagqsqgderfyfpkemldqgnkkhydlfdetyrefssyihngalvlkk

    Sequence, based on observed residues (ATOM records): (download) 
    >4lrlC (C:)
tipykeqrlpiekvfrdpvhnyihvqhqvildlinsaevqrlrrikqlgtssftfhgaeh
srfshslgvyeitrriceifqrnysverlgengwndderlitlcaallhdvghgpyshtf
ehifdtnheaitvqiitspetevyqilnrvsadfpekvasvitkqypnpqvvqmissqid
adrmdyllrdayftgteygtfdltrilrvirpykggiafamngmhavedyivsryqmyvq
vyfhpvsrgmevildhllhrakelfenpefdydlqasllvpffkgdftlqeylklddgvl
styftqwmdvpdsilgdlakrflmrkplksatftnekesaatiaylreliekvgfnpkyy
tainssydlpydfyrpnkdrhrtqielmqkdgslvelatvsplvaalagqsqgderfyfp
kemldqgnkkhydlfdetyrefssyihngalvlkk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4lrlD (D:)
mhhhhhhssgvdlgtenlyfqsnamtipykeqrlpiekvfrdpvhnyihvqhqvildlin
saevqrlrrikqlgtssftfhgaehsrfshslgvyeitrriceifqrnysverlgengwn
dderlitlcaallhdvghgpyshtfehifdtnheaitvqiitspetevyqilnrvsadfp
ekvasvitkqypnpqvvqmissqidadrmdyllrdayftgteygtfdltrilrvirpykg
giafamngmhavedyivsryqmyvqvyfhpvsrgmevildhllhrakelfenpefdydlq
asllvpffkgdftlqeylklddgvlstyftqwmdvpdsilgdlakrflmrkplksatftn
ekesaatiaylreliekvgfnpkyytainssydlpydfyrpnkdrhrtqielmqkdgslv
elatvsplvaalagqsqgderfyfpkemldqgnkkhydlfdetyrefssyihngalvlkk

    Sequence, based on observed residues (ATOM records): (download) 
    >4lrlD (D:)
mtipykeqrlpiekvfrdpvhnyihvqhqvildlinsaevqrlrrikqlgtssftfhgae
hsrfshslgvyeitrriceifqrnysverlgengwndderlitlcaallhdvghgpysht
fehifdtnheaitvqiitspetevyqilnrvsadfpekvasvitkqypnpqvvqmissqi
dadrmdyllrdayftgteygtfdltrilrvirpykggiafamngmhavedyivsryqmyv
qvyfhpvsrgmevildhllhrakelfenpefdydlqasllvpffkgdftlqeylklddgv
lstyftqwmdvpdsilgdlakrflmrkplksatftnekesaatiaylreliekvgfnpky
ytainssydlpydfyrpnkdrhrtqielmqkdgslvelatvsplvaalagqsqgderfyf
pkemldlfdetyrefssyi