PDB entry 4lqw

View 4lqw on RCSB PDB site
Description: Crystal structure of HIV-1 capsid N-terminal domain in complex with NUP358 cyclophilin
Class: isomerase
Keywords: cyclophilin, isomerase, capsid
Deposited on 2013-07-19, released 2013-08-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-02-04, with a file datestamp of 2015-01-30.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.207
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: E3 SUMO-protein ligase RanBP2
    Species: Homo sapiens [TaxId:9606]
    Gene: RANBP2, NUP358
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49792 (9-176)
      • expression tag (8)
    Domains in SCOPe 2.08: d4lqwa1, d4lqwa2
  • Chain 'B':
    Compound: E3 SUMO-protein ligase RanBP2
    Species: Homo sapiens [TaxId:9606]
    Gene: RANBP2, NUP358
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49792 (9-176)
      • expression tag (8)
    Domains in SCOPe 2.08: d4lqwb1, d4lqwb2
  • Chain 'C':
    Compound: capsid protein p24
    Species: Human immunodeficiency virus type 1 [TaxId:11698]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4lqwc_
  • Chain 'D':
    Compound: capsid protein p24
    Species: Human immunodeficiency virus type 1 [TaxId:11698]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4lqwd_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4lqwA (A:)
    mahhhhhhmelsketnpvvffdvcadgeplgritmelfsnivprtaenfralctgekgfg
    fknsifhrvipdfvcqggditkhdgtggqsiygdkfedenfdvkhtgpgllsmanqgqnt
    nnsqfvitlkkaehldfkhvvfgfvkdgmdtvkkiesfgspkgsvcrrititecgqi
    

    Sequence, based on observed residues (ATOM records): (download)
    >4lqwA (A:)
    melsketnpvvffdvcadgeplgritmelfsnivprtaenfralctgekgfgfknsifhr
    vipdfvcqggditkhdgtggqsiygdkfedenfdvkhtgpgllsmanqgqntnnsqfvit
    lkkaehldfkhvvfgfvkdgmdtvkkiesfgspkgsvcrrititecgqi
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4lqwB (B:)
    mahhhhhhmelsketnpvvffdvcadgeplgritmelfsnivprtaenfralctgekgfg
    fknsifhrvipdfvcqggditkhdgtggqsiygdkfedenfdvkhtgpgllsmanqgqnt
    nnsqfvitlkkaehldfkhvvfgfvkdgmdtvkkiesfgspkgsvcrrititecgqi
    

    Sequence, based on observed residues (ATOM records): (download)
    >4lqwB (B:)
    melsketnpvvffdvcadgeplgritmelfsnivprtaenfralctgekgfgfknsifhr
    vipdfvcqggditkhdgtggqsiygdkfedenfdvkhtgpgllsmanqgqntnnsqfvit
    lkkaehldfkhvvfgfvkdgmdtvkkiesfgspkgsvcrrititecgqi
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4lqwC (C:)
    pivqnlqgqmvhqaisprtlnawvkvveekafspevipmfsalsegatpqdlntmlntvg
    ghqaamqmlketineeaaewdrlhpvhagpiapgqmreprgsdiagttstlqeqigwmth
    nppipvgeiykrwiilglnkivrmys
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >4lqwD (D:)
    pivqnlqgqmvhqaisprtlnawvkvveekafspevipmfsalsegatpqdlntmlntvg
    ghqaamqmlketineeaaewdrlhpvhagpiapgqmreprgsdiagttstlqeqigwmth
    nppipvgeiykrwiilglnkivrmys
    

    Sequence, based on observed residues (ATOM records): (download)
    >4lqwD (D:)
    pivqqmvhqaisprtlnawvkvveekafspevipmfsalsegatpqdlntmlntvgghqa
    amqmlketineeaaewdrlhpvhagpiapgqmreprgsdiagttstlqeqigwmthnppi
    pvgeiykrwiilglnkivrmy