PDB entry 4lp0

View 4lp0 on RCSB PDB site
Description: Crystal structure of a topoisomerase ATP inhibitor
Class: isomerase/isomerase inhibitor
Keywords: protein-inhibitor complex, ATP binding, structure-based drug design, antimicrobial, virtual screen, ATPase domain, ISOMERASE-ISOMERASE INHIBITOR complex
Deposited on 2013-07-14, released 2013-11-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-01-15, with a file datestamp of 2014-01-10.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.168
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Topoisomerase IV subunit B
    Species: Streptococcus pneumoniae [TaxId:171101]
    Gene: parE, spr0756
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4lp0a_
  • Heterogens: 1YM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4lp0A (A:)
mskkeininnynddaiqvlegldavrkrpgmyigstdgaglhhlvweivdnavdealsgf
gdridvtinkdgsltvqdhgrgmptgmhamgiptveviftilhaggkfgqggyktsgglh
gvgssvvnalsswleveitrdgavykqrfenggkpvttlkkigtalksktgtkvtfmpda
tifsttdfkyntiserlnesafllknvtlsltdkrtdeaiefhyen

    Sequence, based on observed residues (ATOM records): (download) 
    >4lp0A (A:)
qvlegldavrkrpgmyigstdgaglhhlvweivdnavdealsgfgdridvtinkdgsltv
qdhgrgmptgmhamgiptveviftilhvgssvvnalsswleveitrdgavykqrfenggk
pvttlkkigtalksktgtkvtfmpdatifsttdfkyntiserlnesafllknvtlsltdk
rtdeaiefhyen