PDB entry 4loh

View 4loh on RCSB PDB site
Description: Crystal structure of hSTING(H232) in complex with c[G(2',5')pA(3',5')p]
Class: immune system
Keywords: innate immunity, IMMUNE SYSTEM
Deposited on 2013-07-12, released 2013-08-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-08-05, with a file datestamp of 2015-07-31.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Stimulator of interferon genes protein
    Species: Homo sapiens [TaxId:9606]
    Gene: TMEM173, ERIS, MITA, STING
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q86WV6 (1-End)
      • expression tag (0)
    Domains in SCOPe 2.08: d4loha1, d4loha2
  • Chain 'B':
    Compound: Stimulator of interferon genes protein
    Species: Homo sapiens [TaxId:9606]
    Gene: TMEM173, ERIS, MITA, STING
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q86WV6 (1-End)
      • expression tag (0)
    Domains in SCOPe 2.08: d4lohb1, d4lohb2
  • Heterogens: 1SY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4lohA (A:)
svahglawsyyigylrlilpelqarirtynqhynnllrgavsqrlyillpldcgvpdnls
madpnirfldklpqqtgdhagikdrvysnsiyellengqragtcvleyatplqtlfamsq
ysqagfsredrleqaklfcrtlediladapesqnncrliayqepaddssfslsqevlrhl
rqeekeev

    Sequence, based on observed residues (ATOM records): (download) 
    >4lohA (A:)
svahglawsyyigylrlilpelqarirtynqhynnllrgavsqrlyillpldcgvpdnls
madpnirfldklpqqtgdhagikdrvysnsiyellengqragtcvleyatplqtlfamsq
ysqagfsredrleqaklfcrtlediladapesqnncrliayqepaddssfslsqevlrhl
rqee

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4lohB (B:)
svahglawsyyigylrlilpelqarirtynqhynnllrgavsqrlyillpldcgvpdnls
madpnirfldklpqqtgdhagikdrvysnsiyellengqragtcvleyatplqtlfamsq
ysqagfsredrleqaklfcrtlediladapesqnncrliayqepaddssfslsqevlrhl
rqeekeev

    Sequence, based on observed residues (ATOM records): (download) 
    >4lohB (B:)
svahglawsyyigylrlilpelqarirtynqhynnllrgavsqrlyillpldcgvpdnls
madpnirfldklpqqtgdhagikdrvysnsiyellengqragtcvleyatplqtlfamsq
ysqagfsredrleqaklfcrtlediladapesqnncrliayqepaddssfslsqevlrhl
rqee