PDB entry 4lnc

View 4lnc on RCSB PDB site
Description: Neutron structure of the cyclic glucose bound Xylose Isomerase E186Q mutant
Class: isomerase
Keywords: isomerase, mutant enzyme, metalloenzyme, two metal binding sites
Deposited on 2013-07-11, released 2014-02-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-09-24, with a file datestamp of 2014-09-19.
Experiment type: NEUT+
Resolution: 2.19 Å
R-factor: 0.288
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: xylose isomerase
    Species: Streptomyces rubiginosus [TaxId:1929]
    Gene: XYLA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24300
      • engineered mutation (3)
      • engineered mutation (7)
      • engineered mutation (185)
    Domains in SCOPe 2.07: d4lnca_
  • Heterogens: GLC, MN, MG, DOD

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4lncA (A:)
mnyaptpvdrftfglwtvgwqgrdpfgdatrraldpvesvrrlaelgahgvtfhdddlip
fgssdsereehvkrfrqalddtgmkvpmattnlfthpvfkdggftandrdvrryalrkti
rnidlavelgaetyvawggregaesggakdvrdaldrmkeafdllgeyvtsqgydirfai
epkpnqprgdillptvghalafierlerpelygvnpevgheqmaglnfphgiaqalwagk
lfhidlngqngikydqdlrfgagdlraafwlvdllesagysgprhfdfkpprtedfdgvw
asaagcmrnylilkeraaafradpevqealrasrldelarptaadglqallddrsafeef
dvdaaaargmaferldqlamdhllgarg

    Sequence, based on observed residues (ATOM records): (download) 
    >4lncA (A:)
yaptpvdrftfglwtvgwqgrdpfgdatrraldpvesvrrlaelgahgvtfhdddlipfg
ssdsereehvkrfrqalddtgmkvpmattnlfthpvfkdggftandrdvrryalrktirn
idlavelgaetyvawggregaesggakdvrdaldrmkeafdllgeyvtsqgydirfaiep
kpnqprgdillptvghalafierlerpelygvnpevgheqmaglnfphgiaqalwagklf
hidlngqngikydqdlrfgagdlraafwlvdllesagysgprhfdfkpprtedfdgvwas
aagcmrnylilkeraaafradpevqealrasrldelarptaadglqallddrsafeefdv
daaaargmaferldqlamdhllgar