PDB entry 4llz

View 4llz on RCSB PDB site
Description: Crystal structure of lumiracoxib bound to the apo-mouse-cyclooxygenase-2
Deposited on 2013-07-09, released 2013-10-16
The last revision was dated 2014-02-26, with a file datestamp of 2014-02-21.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.191
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Prostaglandin G/H synthase 2
    Species: Mus musculus [TaxId:10090]
    Gene: Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Prostaglandin G/H synthase 2
    Species: Mus musculus [TaxId:10090]
    Gene: Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
    Database cross-references and differences (RAF-indexed):
  • Heterogens: BOG, NAG, LUR, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4llzA (A:)
anpccsnpcqnrgecmstgfdqykcdctrtgfygencttpefltriklllkptpntvhyi
lthfkgvwnivnnipflrslimkyvltsrsylidspptynvhygyksweafsnlsyytra
lppvaddcptpmgvkgnkelpdskevlekvllrrefipdpqgsnmmfaffaqhfthqffk
tdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgklkyqviggevypptvkdtqv
emiypphipenlqfavgqevfglvpglmmyatiwlrehnrvcdilkqehpewgdeqlfqt
srliligetikiviedyvqhlsgyhfklkfdpellfnqqfqyqnriasefntlyhwhpll
pdtfniedqeysfkqflynnsillehgltqfvesftrqiagrvaggrnvpiavqavakas
idqsremkyqslneyrkrfslkpytsfeeltgekemaaelkalysdidvmelypallvek
prpdaifgetmvelgapfslkglmgnpicspqywkpstfggevgfkiintasiqslicnn
vkgcpftsfnvqdpqptktatinasashsrlddinptvlikrrstel

    Sequence, based on observed residues (ATOM records):
    >4llzA (A:)
anpccsnpcqnrgecmstgfdqykcdctrtgfygencttpefltriklllkptpntvhyi
lthfkgvwnivnnipflrslimkyvltsrsylidspptynvhygyksweafsnlsyytra
lppvaddcptpmgvkgnkelpdskevlekvllrrefipdpqgsnmmfaffaqhfthqffk
tdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgklkyqviggevypptvkdtqv
emiypphipenlqfavgqevfglvpglmmyatiwlrehnrvcdilkqehpewgdeqlfqt
srliligetikiviedyvqhlsgyhfklkfdpellfnqqfqyqnriasefntlyhwhpll
pdtfniedqeysfkqflynnsillehgltqfvesftrqiagrvaggrnvpiavqavakas
idqsremkyqslneyrkrfslkpytsfeeltgekemaaelkalysdidvmelypallvek
prpdaifgetmvelgapfslkglmgnpicspqywkpstfggevgfkiintasiqslicnn
vkgcpftsfnvq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4llzB (B:)
anpccsnpcqnrgecmstgfdqykcdctrtgfygencttpefltriklllkptpntvhyi
lthfkgvwnivnnipflrslimkyvltsrsylidspptynvhygyksweafsnlsyytra
lppvaddcptpmgvkgnkelpdskevlekvllrrefipdpqgsnmmfaffaqhfthqffk
tdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgklkyqviggevypptvkdtqv
emiypphipenlqfavgqevfglvpglmmyatiwlrehnrvcdilkqehpewgdeqlfqt
srliligetikiviedyvqhlsgyhfklkfdpellfnqqfqyqnriasefntlyhwhpll
pdtfniedqeysfkqflynnsillehgltqfvesftrqiagrvaggrnvpiavqavakas
idqsremkyqslneyrkrfslkpytsfeeltgekemaaelkalysdidvmelypallvek
prpdaifgetmvelgapfslkglmgnpicspqywkpstfggevgfkiintasiqslicnn
vkgcpftsfnvqdpqptktatinasashsrlddinptvlikrrstel

    Sequence, based on observed residues (ATOM records):
    >4llzB (B:)
anpccsnpcqnrgecmstgfdqykcdctrtgfygencttpefltriklllkptpntvhyi
lthfkgvwnivnnipflrslimkyvltsrsylidspptynvhygyksweafsnlsyytra
lppvaddcptpmgvkgnkelpdskevlekvllrrefipdpqgsnmmfaffaqhfthqffk
tdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgklkyqviggevypptvkdtqv
emiypphipenlqfavgqevfglvpglmmyatiwlrehnrvcdilkqehpewgdeqlfqt
srliligetikiviedyvqhlsgyhfklkfdpellfnqqfqyqnriasefntlyhwhpll
pdtfniedqeysfkqflynnsillehgltqfvesftrqiagrvaggrnvpiavqavakas
idqsremkyqslneyrkrfslkpytsfeeltgekemaaelkalysdidvmelypallvek
prpdaifgetmvelgapfslkglmgnpicspqywkpstfggevgfkiintasiqslicnn
vkgcpftsfnv