PDB entry 4lly

View 4lly on RCSB PDB site
Description: Crystal structure of Pertuzumab Clambda Fab with variable and constant domain redesigns (VRD2 and CRD2) at 1.6A
Class: immune system
Keywords: Fab, IMMUNE SYSTEM
Deposited on 2013-07-09, released 2014-01-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-06-26, with a file datestamp of 2019-06-21.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: mutated Pertuzumab Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LLY (0-End)
    Domains in SCOPe 2.08: d4llya_
  • Chain 'B':
    Compound: Light chain CLAMBDA
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LLY (0-End)
  • Chain 'C':
    Compound: mutated Pertuzumab Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LLY (0-End)
    Domains in SCOPe 2.08: d4llyc_
  • Chain 'D':
    Compound: Light chain CLAMBDA
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LLY (0-End)
  • Heterogens: GOL, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4llyA (A:)
evqlvesggglvqpggslrlscaasgftftdytmdwvrkapgkglewvadvnpnsggsiy
nqefkgrftlsvdrskntlylqmnslraedtavyycarnlgpsfyfdywgqgtlvtvssa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvatgpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >4llyA (A:)
evqlvesggglvqpggslrlscaasgftftdytmdwvrkapgkglewvadvnpnsggsiy
nqefkgrftlsvdrskntlylqmnslraedtavyycarnlgpsfyfdywgqgtlvtvssa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvatgpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4llyC (C:)
evqlvesggglvqpggslrlscaasgftftdytmdwvrkapgkglewvadvnpnsggsiy
nqefkgrftlsvdrskntlylqmnslraedtavyycarnlgpsfyfdywgqgtlvtvssa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvatgpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >4llyC (C:)
evqlvesggglvqpggslrlscaasgftftdytmdwvrkapgkglewvadvnpnsggsiy
nqefkgrftlsvdrskntlylqmnslraedtavyycarnlgpsfyfdywgqgtlvtvssa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvatgpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'D':
    No sequence available.