PDB entry 4llw

View 4llw on RCSB PDB site
Description: Crystal structure of Pertuzumab Clambda Fab with variable domain redesign (VRD2) at 1.95A
Class: immune system
Keywords: Fab, IMMUNE SYSTEM
Deposited on 2013-07-09, released 2014-01-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-06-26, with a file datestamp of 2019-06-21.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: mutated Pertuzumab Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LLW (0-End)
    Domains in SCOPe 2.08: d4llwa_
  • Chain 'B':
    Compound: Light chain CLAMBDA
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LLW (0-End)
  • Chain 'C':
    Compound: mutated Pertuzumab Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LLW (0-End)
    Domains in SCOPe 2.08: d4llwc_
  • Chain 'D':
    Compound: Light chain CLAMBDA
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 4LLW (0-End)
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4llwA (A:)
evqlvesggglvqpggslrlscaasgftftdytmdwvryapgkglewvadvnpnsggsiy
nqrfkgrftlsvdrskntlylqmnslraedtavyycarnlgpsfyfdywgqgtlvtvssa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >4llwA (A:)
evqlvesggglvqpggslrlscaasgftftdytmdwvryapgkglewvadvnpnsggsiy
nqrfkgrftlsvdrskntlylqmnslraedtavyycarnlgpsfyfdywgqgtlvtvssa
stkgpsvfplapgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssv
vtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4llwC (C:)
evqlvesggglvqpggslrlscaasgftftdytmdwvryapgkglewvadvnpnsggsiy
nqrfkgrftlsvdrskntlylqmnslraedtavyycarnlgpsfyfdywgqgtlvtvssa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >4llwC (C:)
evqlvesggglvqpggslrlscaasgftftdytmdwvryapgkglewvadvnpnsggsiy
nqrfkgrftlsvdrskntlylqmnslraedtavyycarnlgpsfyfdywgqgtlvtvssa
stkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'D':
    No sequence available.