PDB entry 4llq

View 4llq on RCSB PDB site
Description: structure of redesigned igg1 first constant and lambda domains (ch1:clambda constant redesign 2 beta, crd2b) at 1.42a
Deposited on 2013-07-09, released 2014-01-29
The last revision was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 1.42 Å
R-factor: N/A
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: mutated CH1
    Species: Homo sapiens [TaxId:9606]
    Gene: DKFZp686G11190
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6MZQ6
      • engineered mutation (54)
  • Chain 'B':
    Compound: mutated light chain Clambda
    Species: Homo sapiens [TaxId:9606]
    Gene: IGL@
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6PJR7
      • engineered mutation (50)
      • engineered mutation (90)
  • Heterogens: PG6, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4llqA (A:)
maastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtgpavlq
ssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscgshhhhhh

    Sequence, based on observed residues (ATOM records):
    >4llqA (A:)
astkgpsvfplapsstsggtaalgclvkdyfpepvtvswnsgaltsgvhtgpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >4llqB (B:)
mkyllptaaagllllaaqpamagqpkaapsvtlfppsseelqankatlvcaisdfypgav
tvawkadsspvkagvetttpskqsnnkyaawsylsltpeqwkshrsyscqvthegstvek
tvapteclesgketaaakferqhmdsstsaa

    Sequence, based on observed residues (ATOM records):
    >4llqB (B:)
pkaapsvtlfppsseelqankatlvcaisdfypgavtvawkadsspvkagvetttpskqs
nnkyaawsylsltpeqwkshrsyscqvthegstvektvapt